Critical limb ischaemia
When arteries become blocked, slowing or limiting blood flow, it can cause pain and sometimes the loss of a limb. Severe cases of critical limb ischaemia can be life threatening. Around 70% of patients are eligible for surgery; those who are not have had few options other than amputation. But regenerative therapies could change that.
For more on critical limb ischaemia from nature.com, see nature.com/subjects/peripheral-vascular-disease
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