Cancer Genomics

Cancer is a disease of the genome. The past decade has seen breath-taking advances in the characterization of point mutations and structural alterations in a wide range of cancers; all thanks to the next-generation sequencing technologies. Increasingly, the complete genome sequences of a large number of cancer types are being obtained, providing us with a comprehensive view of cancer development. In this Nature special we showcase recent genome-based efforts to construct such genomic profiles of cancer.

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