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Lab Animal presents a series of commissioned articles that address topics in disease models, reproducibility and translation
ranging from the role of the gut microbiome to the business practices of mouse model sharing. Seeking ways to improve predictive validity is the thread that binds the diverse views in this special collection. Cover design by Erin Dewalt
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| Editorial |
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Confidence in preclinical research ppF101 - F102
Published online: 22 March 2017 | doi:10.1038/laban.1252
Full text | PDF (428K) |
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| Reviews |
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Introducing Therioepistemology: the study of how knowledge is
gained from animal research ppF103 - F113
Joseph P Garner, Brianna N Gaskill, Elin M Weber, Jamie Ahloy-Dallaire & Kathleen R Pritchett-Corning
Published online: 22 March 2017 | doi:10.1038/laban.1224
Abstract | Full text | PDF (302K) |
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Microbiota and reproducibility of rodent models ppF114 - F122
Craig L Franklin & Aaron C Ericsson
Published online: 22 March 2017 | doi:10.1038/laban.1222
Abstract | Full text | PDF (112K) |
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Side effects of pain and analgesia in animal experimentation ppF123 - F128
Paulin Jirkof
Published online: 22 March 2017 | doi:10.1038/laban.1216
Abstract | Full text | PDF (180K) |
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The role of the IACUC in ensuring research reproducibility ppF129 - F135
Jerald Silverman, James Macy & Patricia A Preisig
Published online: 22 March 2017 | doi:10.1038/laban.1213
Abstract | Full text | PDF (112K) |
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| Perspectives |
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Laboratory environmental factors and pain behavior: the relevance
of unknown unknowns to reproducibility and translation ppF136 - F141
Jeffrey S Mogil
Published online: 22 March 2017 | doi:10.1038/laban.1223
Abstract | Full text | PDF (160K) |
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Stressed out: providing laboratory animals with behavioral control
to reduce the physiological effects of stress ppF142 - F145
Brianna N Gaskill & Joseph P Garner
Published online: 22 March 2017 | doi:10.1038/laban.1218
Abstract | Full text | PDF (160K) |
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Reproducibility of histopathological findings in experimental
pathology of the mouse: a sorry tail ppF146 - F151
Jerrold M Ward, Paul N Schofield & John P Sundberg
Published online: 22 March 2017 | doi:10.1038/laban.1214
Abstract | Full text | PDF (160K) |
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Improving quality of science through better animal welfare:
the NC3Rs strategy ppF152 - F156
Mark J Prescott & Katie Lidster
Published online: 22 March 2017 | doi:10.1038/laban.1217
Abstract | Full text | PDF (160K) |
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Aggression in group-housed laboratory mice: why can't we solve
the problem? ppF157 - F161
Elin M Weber, Jamie Ahloy Dallaire, Brianna N Gaskill, Kathleen R Pritchett-Corning & Joseph P Garner
Published online: 22 March 2017 | doi:10.1038/laban.1219
Abstract | Full text | PDF (160K) |
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| Commentaries |
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A license to cure? ppF162 - F163
Cathleen Lutz
Published online: 22 March 2017 | doi:10.1038/laban.1221
Full text | PDF
(472K)
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More than 3Rs: the importance of scientific validity for harm-benefit analysis of animal research ppF164 - F166
Hanno Würbel
Published online: 22 March 2017 | doi:10.1038/laban.1220
Full text | PDF
(564K)
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Swine models, genomic tools and services to enhance our understanding of human health and diseases ppF167 - F172
Eric M Walters, Kevin D Wells, Elizabeth C Bryda, Susan Schommer & Randall S Prather
Published online: 22 March 2017 | doi:10.1038/laban.1215
Abstract | Full text | PDF
(172K)
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