Focus on Targeted cancer therapies

Keeping pace with cancer - p1380

doi:10.1038/nm.3395

Full Text - Keeping pace with cancer | PDF (98 KB) - Keeping pace with cancer

Focus on Targeted cancer therapies

Mechanisms of resistance to therapies targeting BRCA-mutant cancers - pp1381 - 1388

Christopher J Lord & Alan Ashworth

doi:10.1038/nm.3369

Abstract - | Full Text - Mechanisms of resistance to therapies targeting BRCA-mutant cancers | PDF (1,241 KB) - Mechanisms of resistance to therapies targeting BRCA-mutant cancers

Focus on Targeted cancer therapies

The quest to overcome resistance to EGFR-targeted therapies in cancer - pp1389 - 1400

Curtis R Chong & Pasi A Jänne

doi:10.1038/nm.3388

Abstract - | Full Text - The quest to overcome resistance to EGFR-targeted therapies in cancer | PDF (1,069 KB) - The quest to overcome resistance to EGFR-targeted therapies in cancer | Supplementary information

Focus on Targeted cancer therapies

Tumor adaptation and resistance to RAF inhibitors - pp1401 - 1409

Piro Lito, Neal Rosen & David B Solit

doi:10.1038/nm.3392

Abstract - | Full Text - Tumor adaptation and resistance to RAF inhibitors | PDF (3,661 KB) - Tumor adaptation and resistance to RAF inhibitors

Focus on Targeted cancer therapies

Unraveling the therapeutic potential of the Hedgehog pathway in cancer - pp1410 - 1422

Dereck Amakye, Zainab Jagani & Marion Dorsch

doi:10.1038/nm.3389

Abstract - | Full Text - Unraveling the therapeutic potential of the Hedgehog pathway in cancer | PDF (1,217 KB) - Unraveling the therapeutic potential of the Hedgehog pathway in cancer

Focus on Targeted cancer therapies

Microenvironmental regulation of tumor progression and metastasis - pp1423 - 1437

Daniela F Quail & Johanna A Joyce

doi:10.1038/nm.3394

Abstract - | Full Text - Microenvironmental regulation of tumor progression and metastasis | PDF (20,354 KB) - Microenvironmental regulation of tumor progression and metastasis

Focus on Targeted cancer therapies

The epigenetics of epithelial-mesenchymal plasticity in cancer - pp1438 - 1449

Wai Leong Tam & Robert A Weinberg

doi:10.1038/nm.3336

Abstract - | Full Text - The epigenetics of epithelial-mesenchymal plasticity in cancer | PDF (1,366 KB) - The epigenetics of epithelial-mesenchymal plasticity in cancer

Focus on Targeted cancer therapies

Tumor metastasis: moving new biological insights into the clinic - pp1450 - 1464

Liling Wan, Klaus Pantel & Yibin Kang

doi:10.1038/nm.3391

Abstract - | Full Text - Tumor metastasis: moving new biological insights into the clinic | PDF (18,835 KB) - Tumor metastasis: moving new biological insights into the clinic