Dynamic materials for tissue engineering

The tissue microenvironment is structurally and dynamically complex. Materials designed to interact with diseased or compromised tissue to induce regeneration, or to act as a scaffold for the production of tissues in the laboratory, thus need to be responsive to the microenvironment. For this, researchers leverage increased knowledge of the importance of the spatiotemporal integration of biomaterials with the tissue environment, as well as latest developments in high-resolution technologies in imaging and in materials synthesis and fabrication. Dynamically responsive materials for use in tissue engineering respond to external stimuli or have inherent properties that trigger the targeted, timed release of integral chemical constituents or of incorporated ligands for the controlled repair or remodelling of surrounding tissue. This collection highlights recent impactful advances, published in Nature-branded journals, in such dynamic biomaterials.

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