Supplements

MicroRNAs

In this supplement

MicroRNAs (miRNAs) are small, non–coding RNAs found in plants and animals. They regulate gene expression by binding to complementary sequences within target mRNAs. The mammalian genome encodes hundreds of miRNAs that collectively affect the expression of about one–third of all genes. This collection showcases the latest papers from Nature that explore the biogenesis, biological effects in both normal and diseased cells, and therapeutic potential of miRNAs.


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Editorial

Editorial

MicroRNAs collection

Angela K. Eggleston


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MicroRNAs collection

Letter

A skin microRNA promotes differentiation by repressing 'stemness'

Rui Yi, Matthew N. Poy, Markus Stoffel & Elaine Fuchs

Nature 452, 225—229 (13 March 2008) doi:10.1038/nature06642


Article

SMAD proteins control DROSHA–mediated microRNA maturation

Brandi N. Davis et al.

Nature 454, 56—61 (3 July 2008) doi:10.1038/nature07086


Article

Widespread changes in protein synthesis induced by microRNAs

Matthias Selbach et al.

Nature 455, 58—63 (4 September 2008) doi:10.1038/nature07228


Letter

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs

Jennifer L. Umbach et al.

Nature 454, 780—783 (7August 2008) doi:10.1038/nature07103


Letter

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

Yvonne Tay, Jinqiu Zhang, Andrew M. Thomson, Bing Lim & Isidore Rigoutsos

Nature 455, 1124—1128 (23 October 2008) doi:10.1038/nature07299


Corrigendum

Nature 458, 538 (26 March 2009) doi:10.1038/nature07880


Article

Endogenous human microRNAs that suppress breast cancer metastasis

Sohail F. Tavazoie et al.

Nature 451, 147—152 (10 January 2008) doi:10.1038/nature06487


Letter

MicroRNA–mediated switching of chromatin–remodelling complexes in neural development

Andrew S. Yoo, Brett T. Staahl, Lei Chen & Gerald R. Crabtree

Nature 460, 642—646 (30 July 2009) doi:10.1038/nature08139


Erratum

Nature 461, 296 (10 September 2009) doi:10.1038/nature08359


Letter

LNA–mediated microRNA silencing in non–human primates

Joacim Elmén et al.

Nature 452, 896—899 (17 April 2008) doi:10.1038/nature06783


Letter

MicroRNA–21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

Thomas Thum et al.

Nature 456, 980—984 (18 December 2008) doi:10.1038/nature07511


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Archive

Letter

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

Saibal Chatterjee & Helge Großhans

Nature 461, 546—549 (24 September 2009) doi:10.1038/nature08349


Article

miR–145 and miR–143 regulate smooth muscle cell fate and plasticity

Kimberly R. Cordes et al.

Nature 460, 705—710 (6 August 2009) doi:10.1038/nature08195


Article

Argonaute HITS–CLIP decodes microRNA—mRNA interaction maps

Sung Wook Chi, Julie B. Zang, Aldo Mele & Robert B. Darnell

Nature 460, 479—486 (23 July 2009) doi:10.1038/nature08170


Letter

Modulation of microRNA processing by p53

Hiroshi I. Suzuki et al.

Nature 460, 529—533 (23 July 2009) doi:10.1038/nature08199


Letter

The RNA—binding protein KSRP promotes the biogenesis of a subset of microRNAs

Michele Trabucchi et al.

Nature 459, 1010—1014 (18 June 2009) doi:10.1038/nature08025


Article

Early origins and evolution of microRNAs and Piwi–interacting RNAs in animals

Andrew Grimson et al.

Nature 455, 1193—1197 (30 October 2008) doi:10.1038/nature07415


Article

The impact of microRNAs on protein output

Daehyun Baek et al.

Nature 455, 64—71 (4 September 2008) doi:10.1038/nature07242


Letter

Mei–P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

Ralph A. Neumüller et al.

Nature 454, 241—245 (10 July 2008) doi:10.1038/nature07014


Letter

Regulation of progenitor cell proliferation and granulocyte function by microRNA–223

Jonathan B. Johnnidis et al.

Nature 451, 1125—1129 (28 February 2008) doi:10.1038/nature06607


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