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C. RICHARD HUTCHINSON SPECIAL ISSUE : NATURAL PRODUCT BIOSYNTHESIS, ENGINEERING & DRUG DISCOVERY RESEARCH
The January 2011 issue of The Journal of Antibiotics is dedicated to the memory of Professor. C. Richard Hutchinson, a pathfinder who made remarkable contributions to modern natural product biology. The special issue provides a diverse collection of Reviews, Original Research Articles and Notes on various aspects of natural product discovery, biosynthesis, engineering, and drug discovery and development, which have been passionately contributed by many of his former students, postdoctoral fellows, collaborators, colleagues and friends. Professor Hutchinson will be remembered for his strength of spirit, zeal for life and new experiences, and his boundless intellectual curiosity. As a tribute to Dr. Hutchinson's distinguished career, the accompanying web focus brings together a collection of articles published in The Journal of Antibiotics, and other related publications.
Dr Hutchinson's Legacy Papers
Nurturing nature: engineering new antibiotics
Jonathan Kennedy & C. Richard Hutchinson
Nature Biotechnology 17: 538 - 539; doi:10.1038/9839
Substrate-assisted catalysis in cytochrome P450eryF FREE
Jill R. Cupp-Vickery, Oksoo Han, C. Richard Hutchinson & Thomas L. Poulos
Nature Structural & Molecular Biology 3: 632 - 637; doi:10.1038/nsb0796-632
Drug Synthesis by Genetically Engineered Microorganisms FREE
C. Richard Hutchinson
Nature Biotechnology 12: 375 - 380; doi:10.1038/nbt0494-375
Selected Papers from the Special Issue
Special issue of The Journal of Antibiotics dedicated to the late Professor C Richard Hutchinson
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Ben Shen and Haruo Ikeda Guest Editors
J Antibiot 64: 3-5; doi:10.1038/ja.2010.158
Short tribute to Dr Hutchinson
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Julian E Davies
J Antibiot 64: 7; doi:10.1038/ja.2010.152
Hutchinson's legacy: keeping on polyketide biosynthesis
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Carlos Olano
J Antibiot 64: 51-57; advance online publication, November 10, 2010; doi:10.1038/ja.2010.126
A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases
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Takayoshi Saruwatari, Alex P Praseuth, Michio Sato, Kohei Torikai, Hiroshi Noguchi and Kenji Watanabe
J Antibiot 64: 9-17; advance online publication, November 24, 2010; doi:10.1038/ja.2010.130
Giant linear plasmids in Streptomyces: a treasure trove of antibiotic biosynthetic clusters
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Haruyasu Kinashi
J Antibiot 64: 19-25; advance online publication, December 8, 2010; doi:10.1038/ja.2010.146
Fundamental functionality: recent developments in understanding the structure–activity relationships of lantibiotic peptides
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Avena C Ross and John C Vederas
J Antibiot 64: 27-34; advance online publication, November 17, 2010; doi:10.1038/ja.2010.136
The biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), the precursor of mC7N units in ansamycin and mitomycin antibiotics: a review
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Heinz G Floss, Tin-Wein Yu and Kenji Arakawa
J Antibiot 64: 35-44; advance online publication, November 17, 2010; doi:10.1038/ja.2010.139
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