Outlook: Parkinson's Disease

Vol. 466, No. 7310 suppl. ppS3-S22

Parkinson's Disease

In this supplement

Like the condition itself, advances in understanding and treating Parkinson's disease have come slowly yet inexorably. Finally, however, we might be near the tipping point. With prevalence predicted to exceed 8 million in the next 20 years, new ways to treat Parkinson's disease are urgently needed.



Parkinson's Disease

Michelle Grayson

Nature 466, S1 (26 August 2010) doi:10.1038/466S2a

Secrets of the shaking palsy

Jim Schnabel

Nature 466, S2 (26 August 2010) doi:10.1038/466S2b

Clue cards

Factors in the genesis of Parkinson's disease

Levodopa: the story so far

Alison Abbott

Nature 466, S6 (26 August 2010) doi:10.1038/466S6a

Parkinson's disease: a model dilemma

M. Flint Beal

Nature 466, S8 (26 August 2010) doi:10.1038/466S8a

Biomarkers: casting the net wide

Rachel Jones

Nature 466, S11 (26 August 2010) doi:10.1038/466S11a

Slowing the decline

Ruth Williams

Nature 466, S13 (26 August 2010) doi:10.1038/466S13a

Treatment frontiers

Kerri Smith

Nature 466, S15 (26 August 2010) doi:10.1038/466S15a




Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

Alexxai V. Kravitz, Benjamin S. Freeze, Philip R. L. Parker et al.

Nature, (07 July 2010) doi:10.1038/nature09159


Missing pieces in the Parkinson's disease puzzle

Jose A Obeso, Maria C Rodriguez-Oroz, Christopher G Goetz et al.

Nature Medicine 16, 653—661 (23 May 2010) doi:10.1038/nm.2165

News and views

Parkinson disease: Depression and anxiety in Parkinson disease

Pablo Martínez-Martín & Javier Damián

Nature Reviews Neurology 6, 243—245 (May 2010) doi:10.1038/nrneurol.2010.49


Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

Wataru Satake, Yuko Nakabayashi, Ikuko Mizuta et al.

Nature Genetics 41, 1303—1307 (2009) doi:10.1038/ng.485


Genome-wide association study reveals genetic risk underlying Parkinson's disease

Javier Simón-Sánchez, Claudia Schulte, Jose M Bras et al.

Nature Genetics 41, 1308—1312 (2009) doi:10.1038/ng.487