Cancer Gene Therapy

Focus 09 October 2018

Modulation of the Immune System to fight cancer

Harnessing the bodies own immune system to fight cancer has become a major strategy as evidenced by the 2018 Nobel Prize in Medicine. Over the past several years, Cancer Gene Therapy has published important articles focusing on new cancer immunotherapy approaches.

Reviews

Immunosuppression in liver tumors: opening the portal to effective immunotherapy
- P Guha
- J Reha
- S C Katz
Review2 Dec 2016 Cancer Gene Therapy
Intraperitoneal immunotherapy: historical perspectives and modern therapy
- W F Morano
- A Aggarwal
- W B Bowne
Review11 Nov 2016 Cancer Gene Therapy
Current status of immunotherapy for gastrointestinal stromal tumor
- Y Tan
- J C Trent
- A E Rosenberg
Review10 Feb 2017 Cancer Gene Therapy
Combinatorial immunotherapy for melanoma
- D D George
- V A Armenio
- S C Katz
Review11 Nov 2016 Cancer Gene Therapy
Myeloid-derived suppressor cells and their role in pancreatic cancer
- M Pergamo
- G Miller
Review2 Dec 2016 Cancer Gene Therapy
T-cell programming in pancreatic adenocarcinoma: a review
- Y D Seo
- V G Pillarisetty
Review2 Dec 2016 Cancer Gene Therapy
Gene-expression profiling to predict responsiveness to immunotherapy
- N B Jamieson
- A V Maker
Review11 Nov 2016 Cancer Gene Therapy

Articles

Anti-tumor immunity elicited by direct intratumoral administration of a recombinant adenovirus expressing either IL-28A/IFN-λ2 or IL-29/IFN-λ1
- K Hasegawa
- M Tagawa
- M Numasaki
Original Article19 Aug 2016 Cancer Gene Therapy
Preclinical evaluation of radiation and systemic, RGD-targeted, adeno-associated virus phage-TNF gene therapy in a mouse model of spontaneously metastatic melanoma
- T J Quinn
- N Healy
- C Guha
Original Article9 Dec 2016 Cancer Gene Therapy
Recipient C6 rs9200 genotype is associated with hepatocellular carcinoma recurrence after orthotopic liver transplantation in a Han Chinese population
- Z Wang
- J Liao
- Z Peng
Original Article13 May 2016 Cancer Gene Therapy
Combination of p53-DC vaccine and rAd-p53 gene therapy induced CTLs cytotoxic against p53-deleted human prostate cancer cells in vitro
- H Saito
- K Kitagawa
- T Shirakawa
Original Article16 Jun 2017 Cancer Gene Therapy
Therapeutic vaccination based on side population cells transduced by the granulocyte–macrophage colony-stimulating factor gene elicits potent antitumor immunity
- C Sakamoto
- H Kohara
- K Tani
Original Article13 Jan 2017 Cancer Gene Therapy
Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases
- M Thorn
- P Guha
- S C Katz
Original Article20 May 2016 Cancer Gene Therapy
Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery
- S C Katz
- G R Point
- R P Junghans
Original Article15 Apr 2016 Cancer Gene Therapy
Immunogenic cell death by oncolytic herpes simplex virus type 1 in squamous cell carcinoma cells
- A Takasu
- A Masui
- Y Yura
Original Article18 Mar 2016 Cancer Gene Therapy
Baculovirus directly activates murine NK cells via TLR9
- T Moriyama
- T Suzuki
- H Takaku
Original Article10 Feb 2017 Cancer Gene Therapy
Chimeric antigen receptors for treatment of glioblastoma: a practical review of challenges and ways to overcome them
- S Sengupta
- G Mao
- P Sampath
Review21 Oct 2016 Cancer Gene Therapy

Editorial

The challenges of solid tumor for designer CAR-T therapies: a 25-year perspective
- Richard P Junghans
Editorial10 Apr 2017 Cancer Gene Therapy

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