Supplements

Regenerative medicine

Vol. 453, No. 7193 pp 301–351

In this supplement

• Editorial
• Introduction
• Reviews

The capacity of most tissues to regenerate derives from stem cells, but there are many barriers to the use of stem-cell-based therapies in the clinic. Such therapies, however, have the potential to improve human health enormously, and knowledge gained from studying cells in culture and in model organisms is now laying the groundwork for a new era of regenerative medicine.

Editorial

Regenerative medicine Free access

Natalie DeWitt

doi:10.1038/453301a

Full Text | PDF (90KB)

Introduction

Regenerative medicine and human models of human disease

Kenneth R. Chien

doi:10.1038/nature07037

Abstract | Full Text | PDF (952KB)

Reviews

Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal

Leonard I. Zon

doi:10.1038/nature07038

Abstract | Full Text | PDF (735KB)

Wound repair and regeneration

Geoffrey C. Gurtner, Sabine Werner, Yann Barrandon & Michael T. Longaker

doi:10.1038/nature07039

Abstract | Full Text | PDF (6,567KB)

Stem-cell-based therapy and lessons from the heart

Robert Passier, Linda W. van Laake & Christine L. Mummery

doi:10.1038/nature07040

Abstract | Full Text | PDF (2,002KB)

Tolerance strategies for stem-cell-based therapies

Ann P. Chidgey, Daniel Layton, Alan Trounson & Richard L. Boyd

doi:10.1038/nature07041

Abstract | Full Text | PDF (2,101KB)

A chemical approach to stem-cell biology and regenerative medicine

Yue Xu, Yan Shi & Sheng Ding

doi:10.1038/nature07042

Abstract | Full Text | PDF (1,770KB)

Imaging stem-cell-driven regeneration in mammals

Timm Schroeder

doi:10.1038/nature07043

Abstract | Full Text | PDF (355KB)