Genetic and epigenetic insights into autoimmunity

Autoimmunity is an underlying cause of many diseases, including type I diabetes mellitus, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus and Crohn’s disease. The processes that govern autoimmune responses are not completely understood, but most researchers agree that a mixture of genetic susceptibility and environmental factors are involved in the development of autoimmunity. The goal of this Collection is to highlight advances from the rapidly evolving fields of genetic and epigenetic research that have increased our understanding of autoimmunity in general and of the pathogenesis of autoimmune diseases across all medical specialties.

This Collection contains Research, Reviews and News articles from several Nature journals that describe the latest advances in genetic and epigenetic research into autoimmunity and autoimmune diseases.

News and Comment