Focus 06 December 2016

Showcasing China

The editors of Laboratory Investigation (LI) are proud to present a Web Focus that showcases research by authors from institutions across China. We selected 20 recent papers to highlight the significant contributions of Chinese scientists to LI and to introduce the journal to an even wider audience.

Content

Laboratory Investigation web focus on China
- Catherine M Ketcham
- Akihiro Umezawa
- Gene P Siegal
Editorial25 Oct 2016 Laboratory Investigation
The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
- Ke Yang
- Xin Wang
- Tong-Chuan He
Pathobiology in Focus30 Nov 2015 Laboratory Investigation
Multifactorial theory applied to the neurotoxicity of paraquat and paraquat-induced mechanisms of developing Parkinson’s disease
- Xiao-feng Zhang
- Mark Thompson
- Yi-hua Xu
Mini Review1 Feb 2016 Laboratory Investigation
Diffuse large B-cell lymphoma: sub-classification by massive parallel quantitative RT-PCR
- Xuemin Xue
- Naiyan Zeng
- Ming-Qing Du
Technical Report24 Nov 2014 Laboratory Investigation
Inactivation of Notch signaling reverses the Th17/Treg imbalance in cells from patients with immune thrombocytopenia
- Shuang Yu
- Chuanfang Liu
- Daoxin Ma
Research Article8 Dec 2014 Laboratory Investigation
Overexpression of stathmin 1 is a poor prognostic biomarker in non-small cell lung cancer
- Wei Nie
- Mi-die Xu
- Bing Li
Research Article10 Nov 2014 Laboratory Investigation
Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis
- Li Zhang
- Xiao-Hong Fu
- Qiang Wang
Research Article10 Nov 2014 Laboratory Investigation
Endogeous sulfur dioxide protects against oleic acid-induced acute lung injury in association with inhibition of oxidative stress in rats
- Siyao Chen
- Saijun Zheng
- Hongfang Jin
Research Article12 Jan 2015 Laboratory Investigation
A modified murine model of systemic sclerosis: bleomycin given by pump infusion induced skin and pulmonary inflammation and fibrosis
- Minrui Liang
- Jiaoyan Lv
- Hejian Zou
Technical Report15 Dec 2014 Laboratory Investigation
HDAC is essential for epigenetic regulation of Thy-1 gene expression during LPS/TLR4-mediated proliferation of lung fibroblasts
- Shunpeng Xing
- Fang Nie
- Zhengyu He
Research Article27 Jul 2015 Laboratory Investigation
Human amniotic mesenchymal stem cells alleviate lung injury induced by ischemia and reperfusion after cardiopulmonary bypass in dogs
- Yong Qiang
- Guiyou Liang
- Limei Yu
Research Article29 Feb 2016 Laboratory Investigation
Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma
- Xiaowei Tang
- Yun Wang
- Stephen J Meltzer
Research Article3 Aug 2015 Laboratory Investigation
MicroRNA-17-5p activates hepatic stellate cells through targeting of Smad7
- Fujun Yu
- Yong Guo
- Jianjian Zheng
Research Article27 Apr 2015 Laboratory Investigation
Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes
- Xiao Zhang
- Guangli Du
- Ping Liu
Research Article21 Dec 2015 Laboratory Investigation
Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy
- Ai-Li Cao
- Li Wang
- Wen Peng
Research Article21 Mar 2016 Laboratory Investigation
Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome
- Qing Wei
- Pengbo Guo
- Lihui Han
Research Article25 May 2015 Laboratory Investigation
Downregulation of TRIM27 expression inhibits the proliferation of ovarian cancer cells in vitro and in vivo
- Yanyan Ma
- Zengtao Wei
- Xiaoyan Wang
Research Article16 Nov 2015 Laboratory Investigation
PIK3C2A is a gene-specific target of microRNA-518a-5p in imatinib mesylate-resistant gastrointestinal stromal tumor
- Yuan Shi
- Xiaodong Gao
- Yingyong Hou
Research Article7 Mar 2016 Laboratory Investigation
microRNA-186 inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma by targeting SKP2
- Wei He
- Jianfang Feng
- Guoqiang Zhao
Research Article16 Nov 2015 Laboratory Investigation
MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis
- Li Xiao
- Xun Zhou
- Lin Sun
Research Article11 May 2015 Laboratory Investigation
PHD/HIF-1 upregulates CA12 to protect against degenerative disc disease: a human sample, in vitro and ex vivo study
- Shuai Chen
- Xiang-Qian Fang
- Shun-Wu Fan
Research Article22 Feb 2016 Laboratory Investigation

Showcasing China

Content

Laboratory Investigation web focus on China

The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies

Multifactorial theory applied to the neurotoxicity of paraquat and paraquat-induced mechanisms of developing Parkinson’s disease

Diffuse large B-cell lymphoma: sub-classification by massive parallel quantitative RT-PCR

Inactivation of Notch signaling reverses the Th17/Treg imbalance in cells from patients with immune thrombocytopenia

Overexpression of stathmin 1 is a poor prognostic biomarker in non-small cell lung cancer

Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis

Endogeous sulfur dioxide protects against oleic acid-induced acute lung injury in association with inhibition of oxidative stress in rats

A modified murine model of systemic sclerosis: bleomycin given by pump infusion induced skin and pulmonary inflammation and fibrosis

HDAC is essential for epigenetic regulation of Thy-1 gene expression during LPS/TLR4-mediated proliferation of lung fibroblasts

Human amniotic mesenchymal stem cells alleviate lung injury induced by ischemia and reperfusion after cardiopulmonary bypass in dogs

Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma

MicroRNA-17-5p activates hepatic stellate cells through targeting of Smad7

Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes

Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy

Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome

Downregulation of TRIM27 expression inhibits the proliferation of ovarian cancer cells in vitro and in vivo

PIK3C2A is a gene-specific target of microRNA-518a-5p in imatinib mesylate-resistant gastrointestinal stromal tumor

microRNA-186 inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma by targeting SKP2

MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis

PHD/HIF-1 upregulates CA12 to protect against degenerative disc disease: a human sample, in vitro and ex vivo study

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