Focus
Focus on Inflammatory disease
- Focus issue:
- July 2015 Volume 21, No 7
There is an emerging understanding of how the disruption of immune homeostasis may lead to the development of chronic inflammatory diseases. This series of articles highlights new data that point toward the influence of environmental factors and addresses recent advances in our knowledge of the cell types and signaling pathways involved in inflammatory disease onset and progression.
Editorial
Focus on Inflammatory disease
Big data meets mechanism -
doi:10.1038/nm.3903
Full Text - Big data meets mechanism | PDF (98 KB) - Big data meets mechanism
News Feature
Focus on Inflammatory disease
A gut feeling about immunity-
Roxanne Khamsi
doi:10.1038/nm.3906
Abstract - | Full Text - A gut feeling about immunity | PDF (331 KB) - A gut feeling about immunity
Reviews
Focus on Inflammatory disease
Influence of nutrient-derived metabolites on lymphocyte immunity -
Marc Veldhoen & Cristina Ferreira
doi:10.1038/nm.3894
Abstract - | Full Text - Influence of nutrient-derived metabolites on lymphocyte immunity | PDF (1,969 KB) - Influence of nutrient-derived metabolites on lymphocyte immunity
Focus on Inflammatory disease
Inflammasomes: mechanism of action, role in disease, and therapeutics -
Haitao Guo, Justin B Callaway & Jenny P-Y Ting
doi:10.1038/nm.3893
Abstract - | Full Text - Inflammasomes: mechanism of action, role in disease, and therapeutics | PDF (2,410 KB) - Inflammasomes: mechanism of action, role in disease, and therapeutics
Focus on Inflammatory disease
Innate lymphoid cells in the initiation, regulation and resolution of inflammation -
Gregory F Sonnenberg & David Artis
doi:10.1038/nm.3892
Abstract - | Full Text - Innate lymphoid cells in the initiation, regulation and resolution of inflammation | PDF (2,587 KB) - Innate lymphoid cells in the initiation, regulation and resolution of inflammation
Focus on Inflammatory disease
IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases -
Michele W L Teng, Edward P Bowman, Joshua J McElwee, Mark J Smyth, Jean-Laurent Casanova, Andrea M Cooper & Daniel J Cua
doi:10.1038/nm.3895
Abstract - | Full Text - IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases | PDF (1,462 KB) - IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases
Focus on Inflammatory disease
The emerging role of resident memory T cells in protective immunity and inflammatory disease -
Chang Ook Park & Thomas S Kupper
doi:10.1038/nm.3883
Abstract - | Full Text - The emerging role of resident memory T cells in protective immunity and inflammatory disease | PDF (1,638 KB) - The emerging role of resident memory T cells in protective immunity and inflammatory disease
Focus on Inflammatory disease
Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies -
Judy Cho & Marc Feldman
doi:10.1038/nm.3897
Abstract - | Full Text - Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies | PDF (505 KB) - Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies
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