Special Issue on Severity in the Genomic Age
- Submission status
- Submission deadline
The concept of the ‘severity’ or ‘seriousness’ of a genetic condition (disease/disorder) is pivotal to determining current, and future, applications of genomic medicine. Yet this concept - which often serves as an access and permissibility “filter” for genomic testing and technologies – remains nebulous and poorly understood. Recent work across a range of disciplines has begun the process of mapping and critically engaging with the contours of this complex phenomenon, taking account of a range of stakeholder perspectives and the varying contexts in which the notion of ‘severity’ is relevant.
This special issue will bring together key work in this area, including outputs from a recent Brocher Foundation workshop ‘Severity in the genomic age: clarification and applications’ (June 2023). This workshop was attended by an international group of researchers, professionals and policy-makers interested in the concept of severity and its applications in genomics.
We welcome submissions to this special issue on a wide range of topics relevant to severity, including but not limited to:
- Normative or ethical reflections on the concept of severity
- The application of severity across different technological applications and contexts
- Measures, classification systems and frameworks for capturing severity, as well as their development and evaluation
- The role and significance of severity within healthcare policy-making and priority setting in the international arena
- The significance/relevance of lived experience, social, environmental and economic contexts to understandings of severity
- How competing versions of severity across stakeholder groups or applications can be weighed or prioritised
We welcome empirical papers, reviews and comment/viewpoint articles. Deadline for submission: 31st January 2024.
Submissions are welcome from authors regardless of whether they attended the Brocher workshop.