Focus on immunometabolism

Over the past decade, “immunometabolism” has become one of the most exciting areas of translational research. Metabolic processes regulate immune cell responses in healthy individuals as well as during infection, cancer, autoimmunity and obesity. Moreover, immune responses are shaped not only by host metabolites, but also by metabolites derived from the microbiota and infectious agents. These discoveries are paving the way for novel therapies for chronic inflammatory and autoimmune diseases, as well representing a new class of cancer immunotherapies.

In this Focus in Nature Reviews Immunology, leading experts discuss the latest developments in the field.

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