Focus
Focus on TCR Signaling
- Focus
- September 2014 Volume 15, No 9
Four specially commissioned Review and Perspective articles that provide an in-depth analysis of T cell receptor (TCR) signaling and the functional consequences of TCR recognition of peptides presented on major histocompatibility complex molecules.
Editorial
Focus on TCR Signaling
A primer on TCR signaling - p789
doi:10.1038/ni.2982
Ligation of the TCR initiates multiple signaling cascades that direct the fate of thymocytes and T cells.
Full Text - A primer on TCR signaling | PDF (189 KB) - A primer on TCR signaling
Perspective
Focus on TCR Signaling
Integrative biology of T cell activation - pp790 - 797
Bernard Malissen, Claude Grégoire, Marie Malissen & Romain Roncagalli
doi:10.1038/ni.2959
Abstract - Integrative biology of T cell activation | Full Text - Integrative biology of T cell activation | PDF (1,168 KB) - Integrative biology of T cell activation
Reviews
Focus on TCR Signaling
Insights into the initiation of TCR signaling - pp798 - 807
Arup K Chakraborty & Arthur Weiss
doi:10.1038/ni.2940
Abstract - Insights into the initiation of TCR signaling | Full Text - Insights into the initiation of TCR signaling | PDF (755 KB) - Insights into the initiation of TCR signaling
Focus on TCR Signaling
Serine-threonine kinases in TCR signaling - pp808 - 814
María N Navarro & Doreen A Cantrell
doi:10.1038/ni.2941
Abstract - Serine-threonine kinases in TCR signaling | Full Text - Serine-threonine kinases in TCR signaling | PDF (844 KB) - Serine-threonine kinases in TCR signaling
Focus on TCR Signaling
The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function - pp815 - 823
Kristin A Hogquist & Stephen C Jameson
doi:10.1038/ni.2938
Abstract - The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function | Full Text - The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function | PDF (766 KB) - The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
© 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.
