COPD

Efforts to improve diagnostic criteria and treatment could help the millions of people with this underdiagnosed respiratory condition.

An imaging biomarker, nerve therapy and other highlights from clinical trials and laboratory studies.

Many people with symptoms of chronic obstructive pulmonary disease don’t meet the criteria for diagnosis. The field is grappling with how to define and treat these patients.

Researchers are beginning to work out the part senescent cells play in the respiratory disease.

Extracellular vesicles released in response to cigarette smoke might trigger chronic obstructive pulmonary disease, but engineered versions could be a treatment.

Many people with chronic obstructive pulmonary disease are given steroids despite a lack of evidence underpinning their use.

A ban on CFCs in the 1980s prompted a rethink of the devices used to deliver respiratory drugs, now new worries and the ongoing problems that some patients have using inhalers are bringing change.

Wildfire pollution can be harmful to those with respiratory conditions, but there is little advice on how to keep safe during these events.

Pneumologist María Victorina López Varela lays bare the scale of work required to prevent and treat COPD in the region.

A genome-wide association study in more than 400,000 individuals identifies 139 new signals for lung function. These variants can predict chronic obstructive pulmonary disease in independent, transancestral cohorts.

Genome-wide analysis of chronic obstructive pulmonary disease identifies 82 loci, 35 of which are new. Integration of gene expression and genomic annotation data shows enrichment of signals in lung tissue, smooth muscle and several lung cell types.