Chemical biology

This Collection highlights a selection of recent studies published in Communications Chemistry relating to the structure, function, modification and detection of biomolecules. The biocatalysis and biosynthesis section features articles that probe mechanisms of enzyme activity, unearth new enzymes from biosynthesis studies, and explore applications in chemical synthesis. The structural biology section showcases new insights into the structure and function of biomolecules from modern analytical and computational chemistry. The chemical probes section features articles that showcase chemical tools for the study of biological function, including probe development, labeling methods and bioimaging. Finally, the medicinal chemistry section highlights advances into target identification and the design and synthesis of new lead compounds.

Pd(II) responsive binding of designed bis-histidine peptide to oncogenic KRAS protein

Biocatalysis and biosynthesis

Structural biology

Chemical probes

Medicinal chemistry