Collection 

Stem Cells: from Single Cells to the Clinic

Recent technological progress has facilitated the study of how embryos develop, how embryonic cells transition between different states, how adult stem cells are maintained and differentiate, at unprecedented resolution. The resulting advances in our understanding of stem cell and developmental biology have opened the door to the engineering of complex tissues and the use of stem cells for therapeutic purposes.

In this collection, we highlight recent papers published across Nature Portfolio journals on topics including embryonic development and stem cells, clinical and translational research, stem cell-based tissue engineering, and tissue stem cells.

A perivascular niche for multipotent progenitors in the fetal testis.

Embryonic Development and Stem Cells

Towards Stem Cells in the Clinic

Stem Cell-Based Tissue Engineering

Tissue Stem Cells