Acta Pharmacologica Sinica

Focus 04 September 2020

40 years of APS

We celebrate the 40^th anniversary of Acta Pharmacologica Sinica (APS) with a series of specially commissioned Reviews and Articles across the diverse areas of the journal’s scope, highlighting the advances made in pharmacological research.

Review

Hypoxia, HIF-1α, and COVID-19: from pathogenic factors to potential therapeutic targets
- Zoya O. Serebrovska
- Elisa Y. Chong
- Lei Xi
Review Article27 Oct 2020 Acta Pharmacologica Sinica
Anti-inflammatory signaling through G protein-coupled receptors
- Yun-jun Ge
- Qi-wen Liao
- Richard D. Ye
Review Article15 Oct 2020 Acta Pharmacologica Sinica
The impact of cannabinoid type 2 receptors (CB2Rs) in neuroprotection against neurological disorders
- Qing Xin
- Fei Xu
- Jie Wu
Review Article6 Oct 2020 Acta Pharmacologica Sinica
Involvement of the secreted protein Metrnl in human diseases
- Zhu-wei Miao
- Wen-jun Hu
- Chao-yu Miao
Review Article30 Sep 2020 Acta Pharmacologica Sinica
Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead
- Hong-Shuo Sun
- F. David Horgen
- Zhong-Ping Feng
Review Article29 Sep 2020 Acta Pharmacologica Sinica
Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine derivatives
- Xiao-lei Zhang
- Zhuo-ming Li
- Dayue D Duan
Review Article23 Sep 2020 Acta Pharmacologica Sinica
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity
- Pu Sun
- Ling-hua Meng
Review Article16 Sep 2020 Acta Pharmacologica Sinica
CP-25, a compound derived from paeoniflorin: research advance on its pharmacological actions and mechanisms in the treatment of inflammation and immune diseases
- Xue-zhi Yang
- Wei Wei
Review Article3 Sep 2020 Acta Pharmacologica Sinica
Metformin and cancer immunity
- Ruixia Ma
- Bin Yi
- Yaguang Xi
Review Article31 Aug 2020 Acta Pharmacologica Sinica
Drug development in targeting ion channels for brain edema
- Zheng-wei Luo
- Andrea Ovcjak
- Hong-shuo Sun
Review Article27 Aug 2020 Acta Pharmacologica Sinica
Targeting the photoreceptor cilium for the treatment of retinal diseases
- Jie Ran
- Jun Zhou
Review Article4 Aug 2020 Acta Pharmacologica Sinica
Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19
- Yuan Huang
- Chan Yang
- Shu-wen Liu
Review Article3 Aug 2020 Acta Pharmacologica Sinica
Mitochondrial Ca²⁺ regulation in the etiology of heart failure: physiological and pathophysiological implications
- Hai-xia Xu
- Su-mei Cui
- Jun Ren
Review Article21 Jul 2020 Acta Pharmacologica Sinica
Phase separation as a therapeutic target in tight junction-associated human diseases
- Shuang Sun
- Jun Zhou
Review Article21 Jul 2020 Acta Pharmacologica Sinica
Overview of therapeutic drug research for COVID-19 in China
- Heng Li
- Li Yang
- Jian-ping Zuo
Review Article17 Jun 2020 Acta Pharmacologica Sinica

Article

Minimal contribution of IP₃R2 in cardiac differentiation and derived ventricular-like myocytes from human embryonic stem cells
- Peng Zhang
- Ji-jun Huang
- Huang-tian Yang
Article9 Oct 2020 Acta Pharmacologica Sinica
α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice
- Xin Chen
- Jie Liu
- Xiao-hui Li
Article24 Sep 2020 Acta Pharmacologica Sinica
Quercetin prevents bone loss in hindlimb suspension mice via stanniocalcin 1-mediated inhibition of osteoclastogenesis
- Yin-bo Niu
- Yuan-yuan Yang
- Qi-bing Mei
Article15 Sep 2020 Acta Pharmacologica Sinica
Free fatty acid receptor 4 (FFA4) activation ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis by increasing regulatory T cells in mice
- So-Eun Son
- Soo-Jin Park
- Dong-Soon Im
Article18 Jun 2020 Acta Pharmacologica Sinica
Blockage of sphingosine-1-phosphate receptor 2 attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice
- Soo-Jin Park
- Dong-Soon Im
Article26 May 2020 Acta Pharmacologica Sinica
Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2
- Meng-meng Ning
- Wen-ji Yang
- Ying Leng
Article12 May 2020 Acta Pharmacologica Sinica
An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9
- Yu-zhe Wang
- Xiao Liu
- Ming-wei Wang
Article27 Apr 2020 Acta Pharmacologica Sinica
Metrnl deficiency decreases blood HDL cholesterol and increases blood triglyceride
- Qi Qi
- Wen-jun Hu
- Chao-yu Miao
Article7 Apr 2020 Acta Pharmacologica Sinica
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4
- Guang-yao Lin
- Lin Lin
- Ming-wei Wang
Article31 Mar 2020 Acta Pharmacologica Sinica

Correspondence

Cobrotoxin could be an effective therapeutic for COVID-19
- Fang Lin
- Paul F. Reid
- Zheng-hong Qin
Correspondence25 Aug 2020 Acta Pharmacologica Sinica
Recombinant human ACE2: potential therapeutics of SARS-CoV-2 infection and its complication
- Xiaocong Pang
- Yimin Cui
- Yizhun Zhu
Correspondence24 Jun 2020 Acta Pharmacologica Sinica

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