Cell-cell communication

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Recent advances in single-cell and spatial-omics technology revealed substantial cellular heterogeneity of multicellular organisms. Direct intercellular communication among distinct or similar cell types plays pivotal roles in maintaining tissue homeostasis. As such, cell competition in general supports tissue development and homeostasis; immune cell interactions with infected or transformed cells often takes place in immune responses; symbiotic communication within the stem cell niche brings benefits to both stromal and stem cells to maintain tissue integrity. To help advance this exciting area, Communications Biology welcomes submissions that contribute to our understanding of cell-cell communication in multicellular organisms. We are particularly interested in direct cell-cell communication in development, adult tissue homeostasis, disease pathogenesis, and ageing. In addition to original research Articles, we will also consider Reviews, Perspectives and Comments covering these topics. All submissions will be subject to the same review process as regular Communications Biology Articles.

This Collection supports and amplifies research related to SDG 3.

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