Gene Editing

In less than 10 years since the seminal paper by Doudna and Charpentier, the discovery of CRISPR as a programmable gene editing tool has revolutionized the therapeutic genome editing field. This was acknowledged last year with the announcement of the Nobel prize in Chemistry and continues to be exemplified by increasing publications on the subject. In the last two years, Gene Therapy has seen a remarkable increase in gene editing papers ranging from the basics, such as the contributions of mitotic gene conversion through to in vivo editing of Tay Sachs and Sandoff disease. In this collection, we have selected the most recent papers making a contribution to this exciting field.