Series 

Adult stem cells

Adult stem cells (also known as somatic stem cells or tissue stem cells) are rare populations of cells that are found in the body throughout the majority of postnatal life and give rise to a limited number of mature cell types that build the tissue in which they reside. Their progeny replaces cells that are lost owing to tissue turnover or injury, thus ensuring the maintenance of tissue homeostasis. Well-studied examples in mammals include blood, skin, intestine and muscle stem cells, but it is not clear whether all organs contain dedicated tissue-specific stem cells. This series looks at the progress that has been made in identifying stem cells in different tissues and in understanding their regulation during normal tissue turnover and following injury.

 

 

Intestinal epithelium showing different cell types, including crypt stem cells.

Article series explore a specific theme and comprise commissioned Reviews, Perspectives and Comments that are published consecutively over a period of time.

Click below to access new content added to ongoing series.

Molecular ageing
Started 2019

Cell death
Started 2019

Translation and protein quality control
Started 2017

Metabolic signalling
Started 2017

RNA processing and modifications
Started 2016

Adult stem cells
Started 2015

Technologies and techniques
Started 2014

Cell death and autophagy
2013 -- 2018

DNA damage
Started 2012

Post-translational modifications
Started 2011