Asian Study: Current evidence and perspectives for hypertension management in Asia

Special Issue - Asian Study: Current evidence and perspectives for hypertension management in Asia

Agreement regarding overcoming hypertension in the Asian Hypertension Society Network 2022
- Satoshi Hoshide
- Koichi Yamamoto
- Hiromi Rakugi
JSH Statement14 Oct 2022 Hypertension Research
Exploratory study on the relationship between urinary sodium/potassium ratio, salt intake, and the antihypertensive effect of esaxerenone: the ENaK Study
- Tomohiro Katsuya
- Yoshito Inobe
- on behalf of the ENaK investigators
ArticleOpen Access11 Jan 2024 Hypertension Research
sFlt-1/PIGF ratio positive associated with non-dipper type change in ambulatory blood pressure monitoring(ABPM) for preeclampsia development
- Yunshan Chen
- Xiaodan Di
- Huishu Liu
ArticleOpen Access28 Nov 2023 Hypertension Research
Hypertensive disorders of pregnancy and the risk of dementia: a systematic review and meta-analysis of cohort studies
- Ahmed Arafa
- Rena Kashima
- Yoshihiro Kokubo
Article1 Dec 2023 Hypertension Research
Association between anthropometric indices and 5-year hypertension incidence in the general Japanese population

A total of 41,902 participants from health checkup programs were stratified by gender and age to investigate the association between baseline anthropometric indices and hypertension incidence over a 5-year period. BMI, WC, and BRI were almost equally effective and showed a better association with risk of developing hypertension in women and young adults compared to men and old adults. Conversely, ABSI showed no greater association than BMI or WC in any age group in both men and women. ABSI, a body shape index; AUC, area under the curve from receiver operating characteristic curve analysis; BMI, body mass index; BRI, body roundness index; WC, waist circumference.
- Shin Kawasoe
- Takuro Kubozono
- Mitsuru Ohishi
Article15 Nov 2023 Hypertension Research
The association of triglyceride-glucose index and related parameters with hypertension and cardiovascular risk: a cross-sectional study
- Huanhuan Miao
- Zhanyang Zhou
- Yuqing Zhang
Article27 Nov 2023 Hypertension Research
More rapid progression of brain atrophy in patients on peritoneal dialysis compared with hemodialysis: The VCOHP Study

We demonstrated that decline in GMR progressed significantly more rapidly in PD patients than HD patients independent of potential confounding factors. GMR gray matter volume ratio, HD hemodialysis, PD peritoneal dialysis.
- Kazuhiko Tsuruya
- Hisako Yoshida
- Takanari Kitazono
Article20 Dec 2023 Hypertension Research
Blood pressure variability and outcome in atherosclerosis versus cardioembolism cerebral large vessel occlusion after successful thrombectomy
- Hao Wang
- Yapeng Guo
- Zhiming Zhou
Article17 Nov 2023 Hypertension Research
Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation
- Tatsuya Maruhashi
- Masato Kajikawa
- Yukihito Higashi
Article15 Nov 2023 Hypertension Research
Hypertension combined with atherosclerosis increases the risk of heart failure in patients with diabetes
- Lili Wu
- Jingli Gao
- Jiang Hong
Article15 Dec 2023 Hypertension Research
Calcium channel blockers may reduce the development of long COVID in females
- Takuya Ozawa
- Ryusei Kimura
- Koichi Fukunaga
Article17 Nov 2023 Hypertension Research
The impact of superselective adrenal artery embolization on renal function in patients with primary aldosteronism: a prospective cohort study
- Ze-Qun Lai
- Yang Fu
- Yi-Fei Dong
Article13 Nov 2023 Hypertension Research
Blood pressure in the longevous population with different status of hypertension and frailty
- Huai-Yu Wang
- Jinwei Wang
- Min Chen
Article20 Nov 2023 Hypertension Research
Effects of esaxerenone, a nonsteroidal mineralocorticoid receptor blocker, independent of urinary sodium/potassium ratio and salt intake
- Satoshi Morimoto
- Atsuhiro Ichihara
Comment25 Jan 2024 Hypertension Research
Placental hypoxia, high nighttime blood pressure, and maternal health
- Martin R. Salazar
Comment5 Jan 2024 Hypertension Research
Dementia: a looming threat for women with hypertensive disorders of pregnancy?
- Makiko Abe
- Hisatomi Arima
Comment9 Feb 2024 Hypertension Research
Indicators of insulin resistance in clinical practice
- Nobuo Sasaki
- Yoshitaka Ueno
- Yukihito Higashi
Comment4 Jan 2024 Hypertension Research
Brain atrophy in patients on peritoneal dialysis treatment
- Tetsu Akimoto
Comment5 Jan 2024 Hypertension Research
The necessity of investigations to clarify sex and racial disparities in pathophysiology of Long COVID
- Chisa Matsumoto
Comment31 Jan 2024 Hypertension Research
Systemic hemodynamic atherothrombotic syndrome: from hypothesis to evidence
- Yusuke Ishiyama
- Satoshi Hoshide
- Kazuomi Kario
Review Article13 Oct 2023 Hypertension Research
The association between depressive symptoms and masked hypertension in participants with normotension measured at research center

Depressive symptoms were associated with masked hypertension in individuals with normotension measured at research center.
- Sayuri Tokioka
- Naoki Nakaya
- Atsushi Hozawa
ArticleOpen Access31 Oct 2023 Hypertension Research
The impact of clinical inertia on uncontrolled blood pressure in treated hypertension: real-world, longitudinal data from Japan
- Michihiro Satoh
- Tomoko Muroya
- Hirohito Metoki
Article23 Oct 2023 Hypertension Research
Aldosteronism is associated with more severe cerebral small vessel disease in hypertensive intracerebral hemorrhage
- Bo-Ching Lee
- Hsin-Hsi Tsai
- TAIPAI study group
Article22 Nov 2023 Hypertension Research
The impact of blood pressure variability on the development of parenchymal hematoma in acute cerebral infarction with atrial fibrillation
- Meng-Ni Wu
- Yu-Peng Liu
- Hsiu-Fen Lin
Article23 Oct 2023 Hypertension Research
Pretreatment body mass index affects achievement of target blood pressure with sodium-glucose cotransporter 2 inhibitors in patients with type 2 diabetes mellitus and chronic kidney disease

Pretreatment BMI affects the antihypertensice effect of SGLT2 inhibirors in patients with T2DM and CKD.
- Shunichiro Tsukamoto
- Kazuo Kobayashi
- Akira Kanamori
Article17 Oct 2023 Hypertension Research
Prognostic significance of hypertension history and blood pressure on admission in Japanese patients with coronavirus disease 2019: integrative analysis from the Japan COVID-19 Task Force
- Kaori Sakurai
- Shotaro Chubachi
- Koichi Fukunaga
Article2 Nov 2023 Hypertension Research
The impact of dietary and sleep rhythms on blood pressure in children and adolescents: a cross-sectional study

The optimal dietary rhythm was defined by the indexes of breakfast time, dinner time and daily feeding window. As good meal patterns are defined as satisfied the following three items: for children younger than 12 years should have breakfast after 7:30 am; aged 12 years and over should have breakfast after 7 am; having dinner before 6 pm; daily feeding window less than 12.5 h. And less optimal dietary rhythm should satisfy any condition or eat dinner between 6 pm and 8 pm; and poor dietary rhythm should not satisfy any of the three criteria and eat dinner after 8 pm. Children with optimal dietary rhythm (in group A) had lower SBP (P < 0.001), DBP (P = 0.002) and MAP (P < 0.001) than those in group C.
- Xiaohua Liang
- Xiangqian He
- Zhilian Peng
Article2 Nov 2023 Hypertension Research
A high level of thyroid-stimulating hormone is a risk factor for the development of chronic kidney disease in men: a 10-year cohort study
- Keisuke Endo
- Marenao Tanaka
- Masato Furuhashi
Article16 Oct 2023 Hypertension Research
The association between the estimated glomerular filtration rate and cognitive impairment: the Suita Study
- Ahmed Arafa
- Haruna Kawachi
- Yoshihiro Kokubo
Brief Communication23 Oct 2023 Hypertension Research
Possible relationship between primary aldosteronism and small vessel disease
- Tatsuya Haze
- Kouichi Tamura
Comment22 Nov 2023 Hypertension Research
Blood pressure variability in acute ischemic stroke
- Kenichi Todo
Comment4 Jan 2024 Hypertension Research
Who benefits from the blood pressure-lowering effects of SGLT2 inhibitors in patients with type 2 diabetes mellitus and chronic kidney disease? — Obese or non-obese?
- Kazuki Shiina
Comment15 Dec 2023 Hypertension Research
Association between blood pressure and COVID-19 severity
- Fumiki Yoshihara
Comment25 Dec 2023 Hypertension Research
Cognitive impairment in heart failure patients: association with abnormal circadian blood pressure rhythm: a review from the HOPE Asia Network

Proposed pathways of cognitive impairment in heart failure through abnormal circadian blood pressure rhythm.
- Takahiro Komori
- Satoshi Hoshide
- HOPE Asia Network
Review Article26 Sep 2023 Hypertension Research
Obstructive sleep apnea and non-dipper: epiphenomena or risks of Alzheimer’s disease?: a review from the HOPE Asia Network
- Michiaki Nagai
- Keigo Dote
- on behalf of the HOPE Asia Network
Review Article24 Oct 2023 Hypertension Research
Percentage of mean arterial pressure as a marker of atherosclerosis for detecting patients with coronary artery disease
- Tatsuya Maruhashi
- Masato Kajikawa
- Yukihito Higashi
ArticleOpen Access4 Oct 2023 Hypertension Research
Minor stroke patients with mild-moderate diastolic blood pressure derive greater benefit from dual antiplatelet therapy
- Tingting Liu
- Yongle Wang
- Xiaoyuan Niu
ArticleOpen Access5 Sep 2023 Hypertension Research
Associations for progression of cerebral small vessel disease burden in healthy adults: the Kashima scan study
- Toshihiro Ide
- Yusuke Yakushiji
- Hideo Hara
Article6 Sep 2023 Hypertension Research
A controlled trial of percutaneous adrenal arterial embolization for hypertension in patients with idiopathic hyperaldosteronism
- Yaqiong Zhou
- Xinquan Wang
- Peijian Wang
Article29 Aug 2023 Hypertension Research
The objectively measured walking speed and risk of hypertension in Chinese older adults: a prospective cohort study
- Biying Zhou
- Zhenger Fang
- Guang Hao
Article4 Oct 2023 Hypertension Research
Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia

This article summarizes and discuss recent findings on: 1) A high dietary magnesium intake was associated with a lower prevalence of hypertension; 2) An inverse relationship between dietary magnesium with diabetes hyperlipidemia; 3) Monitoring and management of magnesium was important.
- Mengying Han
- Yixin Zhang
- Yanan Ma
Article11 Oct 2023 Hypertension Research
Impact of sleep-disordered breathing on overnight changes in arterial stiffness in patients with acute heart failure
- Shoichiro Yatsu
- Takatoshi Kasai
- Tohru Minamino
Article2 Oct 2023 Hypertension Research
Prevalence of true resistant hypertension in those referred for uncontrolled hypertension in Malaysia: A comparison using different definitions
- John Jui Ping Yeo
- Leh Siang Yeo
- Alan Yean Yip Fong
Brief Communication6 Sep 2023 Hypertension Research
Adrenal arterial embolization: a possible new treatment for patients with primary aldosteronism
- Kenichi Yokota
Comment12 Oct 2023 Hypertension Research
High blood pressure and colorectal cancer mortality in a 29-year follow-up of the Japanese general population: NIPPON DATA80
- Takashi Hisamatsu
- Aya Kadota
- for the NIPPON DATA80 Research Group
Article22 Nov 2023 Hypertension Research
Nocturnal systolic blood pressure dipping and progression of chronic kidney disease
- Cheol Ho Park
- Jong Hyun Jhee
- Tae-Hyun Yoo
Article14 Jul 2023 Hypertension Research
Urinary Na/K ratio is a predictor of developing chronic kidney disease in the general population
- Hiroyuki Takase
- Naomi Kawakatsu
- Yasuaki Dohi
Article16 Sep 2023 Hypertension Research
Kidney function predicts new-onset cardiorenal events and mortality in primary aldosteronism: approach of the 2021 race-free eGFR equation

Even with the glomerular hyperfiltration phenomenon, baseline eGFR in patients with primary aldosteronism is associated with subsequent cardiorenal outcomes. The results also firstly point to the validity of the 2021 race-free CKD-EPI eGFR equation in healthcare and clinical decision-making.
- Chun-Fu Lai
- Yen-Hung Lin
- the TAIPAI study group
Article16 Sep 2023 Hypertension Research
Sodium-to-potassium ratio and renal functional decline
- Yasuharu Tabara
Comment16 Sep 2023 Hypertension Research
No “U-shaped” associations of estimated glomerular filtration rate with adverse cardiovascular outcomes in patients with primary aldosteronism
- Yuichi Yoshida
- Hirotaka Shibata
Comment9 Nov 2023 Hypertension Research
Home blood pressure-centered approach – from digital health to medical practice: HOPE Asia Network consensus statement 2023
- Kazuomi Kario
- Naoko Tomitani
- Ji-Guang Wang
Review Article21 Aug 2023 Hypertension Research
Anticoagulant therapy and home blood pressure-associated risk for stroke/bleeding events in elderly patients with non-valvular atrial fibrillation: the sub-cohort study of ANAFIE registry
- Kazuomi Kario
- Naoyuki Hasebe
- Hiroshi Inoue
ArticleOpen Access11 Jul 2023 Hypertension Research
New-onset postpartum hypertension in women without a history of hypertensive disorders of pregnancy: a multicenter study in Japan
- Takafumi Ushida
- Noriyuki Nakamura
- Tomomi Kotani
Article18 Jul 2023 Hypertension Research
Prescription of renin-angiotensin system inhibitors in Japan during the COVID-19 pandemic: interrupted time series study
- Ryosuke Miura
- Kouji Okada
Article18 Jul 2023 Hypertension Research
A novel clinical-imaging nomogram for predicting primary aldosteronism in patients with hypertension
- Yuqing Liu
- Min Wang
- Min Sun
Article24 Jul 2023 Hypertension Research
Associations of blood pressure trajectories in early life with target organ damage in midlife : a 30-year cohort study

LVH, left Ventricular Hypertrophy; CA, carotid atherosclerosis; SRD, subclinical renal damage; TOD, target organ damage.
- Wenling Zheng
- Jianjun Mu
- Dan Luo
Article8 Aug 2023 Hypertension Research
Visit-to-visit blood pressure variability and the risk of cardiovascular disease: a prospective cohort analysis
- Shouling Wu
- Xue Tian
- Anxin Wang
Article24 Aug 2023 Hypertension Research
An increase in calculated small dense low-density lipoprotein cholesterol predicts new onset of hypertension in a Japanese cohort
- Marenao Tanaka
- Tatsuya Sato
- Masato Furuhashi
Article2 Aug 2023 Hypertension Research
Postpartum hypertension-The need for definition and classification
- Asako Mito
Comment30 Aug 2023 Hypertension Research
The potential of a new nomogram for the diagnosis of primary aldosteronism
- Tatsuya Haze
Comment15 Aug 2023 Hypertension Research
Long-term changes in blood pressure and their health impact
- Takahisa Murakami
- Michihiro Satoh
- Hirohito Metoki
Comment29 Sep 2023 Hypertension Research
Cross-sectional survey of hypertension management in clinical practice in Japan: the Kanagawa Hypertension Study 2021 conducted in collaboration with Japan Medical Association Database of Clinical Medicine
- Kazuo Kobayashi
- Keiichi Chin
- Akira Kanamori
Article2 Aug 2023 Hypertension Research
Achievement rate of target blood pressure in patients with hypertension treated by hypertension specialists and non-specialists in a real-world setting

For all patients, the target blood pressure (BP) achievement rate were 51.8%. Hypertension specialists and good medication adherence were positive factors in achieving target BP; conversely, obesity, diabetes mellitus, chronic kidney disease, and high urinary salt excretion were inverse factors in achieving target BP among patients with hypertension.
- Atsushi Sakima
- Masanobu Yamazato
- Yusuke Ohya
Article6 Jul 2023 Hypertension Research
The use of anti-adrenergic agents as a predictor of acute kidney injury and delayed recovery of kidney function: the NARA-AKI cohort study
- Masatoshi Nishimoto
- Miho Murashima
- Kazuhiko Tsuruya
Article27 Jun 2023 Hypertension Research
Relationship between the lower limit of systolic blood pressure target and kidney function decline in advanced chronic kidney disease: an instrumental variable analysis from the REACH-J CKD cohort study
- Shimon Kurasawa
- Yoshinari Yasuda
- the REACH-J CKD collaborators
Article18 Jul 2023 Hypertension Research
Association between visceral fat mass and arterial stiffness among community-based screening participants

Visceral fat area and anthropometric indices, except a body-shaped index, were inversely associated with brachial-ankle pulse wave velocity but positively associated with metabolic syndrome components, including hypertension, dyslipidemia, and hyperglycemia.
- Akio Ishida
- Hirona Taira
- Yusuke Ohya
Article23 Jun 2023 Hypertension Research
Hypertension paradox in Japan: the road ahead
- Shigeru Shibata
Comment29 Aug 2023 Hypertension Research
Can we obtain a reliable marker that shows the hypoxic burden in patients with sleep disordered breathing?
- Shin-ichi Ando
Comment6 Sep 2023 Hypertension Research
Longitudinal study of dietary patterns and hypertension in adults: China Health and Nutrition Survey 1991–2018
- Jiguo Zhang
- Wenwen Du
- Huijun Wang
ArticleOpen Access19 Jun 2023 Hypertension Research
Use of calcium channel blockers and risk of breast cancer among women aged 55 years and older: a nationwide population-based cohort study
- Shin-Yi Lin
- Hsin-Yi Huang
- Chi-Chuan Wang
Article30 May 2023 Hypertension Research
Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results
- Ren Mizoguchi
- Shigehiro Karashima
- Kenji Satou
Article6 Jun 2023 Hypertension Research
Overnight changes in uric acid, xanthine oxidoreductase and oxidative stress levels and their relationships with sleep-disordered breathing in patients with coronary artery disease
- Megumi Shimizu
- Takatoshi Kasai
- Hiroyuki Daida
Article31 May 2023 Hypertension Research
Control status of ambulatory blood pressure and its relationship with arterial stiffness in the China nationwide registry of treated hypertensive patients: the REACTION-ABP study
- Ming-Xuan Li
- Dong-Yan Zhang
- Ji-Guang Wang
Article12 Jun 2023 Hypertension Research
Use of calcium channel blockers does not increase breast cancer risk: findings from a nationwide population-based cohort study in Taiwan
- Shintaro Minegishi
Comment27 Jul 2023 Hypertension Research
Association between the gut microbiome and the renin-angiotensin-aldosterone system: a possible link via the activation of the immune system
- Koro Gotoh
- Hirotaka Shibata
Comment1 Aug 2023 Hypertension Research
Associations between IGFBP1 gene polymorphisms and the risk of preeclampsia and fetal growth restriction
- Xianglan Peng
- Dong He
- Hong He
Article22 May 2023 Hypertension Research
The associations between hematological parameters and the incidence of prehypertension and hypertension in children and adolescents: a prospective cohort study
- Lan Huang
- Cui Song
- Xiaohua Liang
Article15 May 2023 Hypertension Research
Brachial-ankle pulse wave velocity is a stronger predictor than blood pressure for atherosclerotic cardiovascular diseases and all-cause mortality: a cohort study

baPWV is a more ideal screening method for ASCVD in large-scale population.
- Yingping Yang
- Dankang Li
- Yaohua Tian
Article26 May 2023 Hypertension Research
Longitudinal association of hypertension and dyslipidemia with cognitive function in community-dwelling older adults: the SONIC study

In the SONIC study, which is an epidemiological study of Japanese older persons aged 70 years or older, a disease-specific examination suggested that high HDL and DBP levels of individuals with hypertension & dyslipidemia and high SBP levels of individuals with hypertension were associated with maintaining cognitive function in community-dwelling older adults
- Yuko Nakamura
- Mai Kabayama
- Kei Kamide
ArticleOpen Access24 Apr 2023 Hypertension Research
Children who appeared or remained overweight or obese predict a higher follow-up blood pressure and higher risk of hypertension: a 6-year longitudinal study in Yantai, China

Children who appeared or remained overweight or obese predict a higher follow-up blood pressure and higher risk of hypertension, whereas losing weight could reduce blood pressure and the risk of hypertension
- Yixin Cui
- Fan Zhang
- Xiaoli Shen
Article24 Apr 2023 Hypertension Research
Obesity and hypertension from a public health perspective in a small remote island of Okinawa, Japan

A community-based, cross-sectional study in 456 residents aged ≥18 years in Yonaguni island, Okinawa prefecture, Japan.
- Yumeno Fukumine
- Koshi Nakamura
Article15 May 2023 Hypertension Research
Cross-classification by systolic and diastolic blood pressure levels and chronic kidney disease, proteinuria, or kidney function decline
- Tsukasa Suenaga
- Michihiro Satoh
- Hirohito Metoki
Article30 Mar 2023 Hypertension Research
Associations of ambient manganese exposure with brain gray matter thickness and white matter hyperintensities
- Shinyoung Woo
- Young Noh
- Changsoo Kim
Article25 Apr 2023 Hypertension Research
How should we manage hypertension and dyslipidemia to maintain cognitive function in older adults?
- Yuichi Akasaki
- Mitsuru Ohishi
Comment29 May 2023 Hypertension Research
Manganese exposure is a risk for brain atrophy
- Masaki Mogi
Comment9 Jun 2023 Hypertension Research
Sympathetic nervous activation and hypertension
- Satoshi Hoshide
- Masaki Mogi
- Kazuomi Kario
Editorial5 Jul 2023 Hypertension Research
Current realities of home blood pressure monitoring from physicians’ perspectives: results from Asia HBPM survey 2020

The recognition of HBPM as a valuable tool for the diagnosis and management of hypertension is suboptimal among both physicians and patients in Asia. A clear and consistent guidance for proper HBPM practice and use of validated and calibrated HBP monitors are among the top priorities to support the integration of HBPM into daily patient care. HBPM: home blood pressure monitoring, HBP: home blood pressure.
- Tzung-Dau Wang
- Takayoshi Ohkubo
- Yutaka Imai
ArticleOpen Access11 Apr 2023 Hypertension Research
Cardiovascular physiological effects of balneotherapy: focused on seasonal differences

We demonstrated the study enrollment, the hot-spring contents and location, and physiological changes of general trends or seasonal variations, which may indicate potential benefits and risks during and after bathing. (Abbreviations: BP, blood pressure; PP, pulse pressure; LV, left ventricular; CO, cardiac output; HR, heart rate; cSBP, central systolic blood pressure; cDBP, central diastolic blood pressure).
- Po-Chun Wang
- Qiao-Chu Song
- Ta-Chen Su
Article29 Mar 2023 Hypertension Research
Association of blood pressure and hyperuricemia with proteinuria and reduced renal function in the general population
- Masako Kochi
- Kentaro Kohagura
- Yusuke Ohya
Article29 Mar 2023 Hypertension Research
The associations of adipokines with hypertension in youth with cardiometabolic risk and the mediation role of insulin resistance: The BCAMS study
- Bo Li
- Cong Hou
- Shan Gao
Article8 Mar 2023 Hypertension Research
Impact of diabetic status and contribution of office and home blood pressure across diabetic status for cardiovascular disease: the J-HOP study

Our study demonstrated the impact of prediabetes and diabetes on CVD and the impact of office and home BP on CVD events in each group.
- Daisuke Suzuki
- Satoshi Hoshide
- Kazuomi Kario
Article8 Mar 2023 Hypertension Research
Asthma and increased risk of myocardial infarction and mortality among hypertensive Korean patients
- Chan Joo Lee
- Jinseub Hwang
- Sungha Park
Article29 Mar 2023 Hypertension Research
Effects of hot spring bathing on cardiac and vascular function
- Satoko Ojima
- Mitsuru Ohishi
Comment25 Apr 2023 Hypertension Research
Hyperuricemia: the third key player for nephrosclerosis with ischemia
- Tadashi Sofue
Comment20 Apr 2023 Hypertension Research
Seasonal variation in blood pressure and its impact on target organ damage and cardiovascular disease incidence
- Keisuke Narita
- Kazuomi Kario
Comment28 Apr 2023 Hypertension Research
Primary aldosteronism and obstructive sleep apnea: the strong ties between them
- Akira Sugawara
- Hiroki Shimada
- Atsushi Yokoyama
Comment9 May 2023 Hypertension Research
Topics 2023 in Hypertension Research leading to guidelines in Asia
- Kazuomi Kario
- Satoshi Hoshide
- Masaki Mogi
Editorial5 Jun 2023 Hypertension Research
Does the place of residence influence your risk of being hypertensive? A study-based on Nepal Demographic and Health Survey
- Ishor Sharma
- M. Karen Campbell
- Saverio Stranges
ArticleOpen Access8 Mar 2023 Hypertension Research
Fat mass as an important predictor of persistent hypertension in patients with primary aldosteronism after adrenalectomy
- Wei-Chieh Huang
- Ying-Ying Chen
- Vin-Cent Wu
Article9 Feb 2023 Hypertension Research
Prevalence of primary aldosteronism in patients with concomitant hypertension and obstructive sleep apnea, baseline data of a cohort
- Mulalibieke Heizhati
- Xiayire Aierken
- Nanfang Li
Article7 Mar 2023 Hypertension Research
Systolic blood pressure, low-density lipoprotein cholesterol levels, and adverse kidney outcome: results from KNOW-CKD
- Kyung Won Kim
- Hee Byung Koh
- Seung Hyeok Han
Article27 Feb 2023 Hypertension Research
Intravascular ultrasound provides additional insights in the hypertensive patients with focal renal artery fibromuscular dysplasia

We investigated whether using an IVUS would provide additional insights in the hypertensive patients with focal renal artery FMD. A new classification of focal renal artery FMD into IMT or NR subtype based on IVUS was described. Renal FMD Patients with IMT subtype were more likely to achieve cure of hypertension.
- Yuanyuan Kang
- Qihong Wu
- Jiguang Wang
Article10 Feb 2023 Hypertension Research
Febuxostat and renal outcomes: post-hoc analysis of a randomized trial
- Kentaro Kohagura
- Sunao Kojima
- on behalf of the Febuxostat for Cerebral and Cardiorenovascular Events Prevention Study (FREED) investigators
Brief Communication7 Feb 2023 Hypertension Research
Association of triglycerides to high-density lipoprotein cholesterol ratio with incident cardiovascular disease but not end-stage kidney disease among patients with biopsy-proven diabetic nephropathy
- Takayuki Uemura
- Masatoshi Nishimoto
- Kazuhiko Tsuruya
Article7 Feb 2023 Hypertension Research
Seasonality in nighttime blood pressure and its associations with target organ damage

Our study shows that there is indeed seasonal variability in nighttime blood pressure, highest in summer and lowest in winter, and its association with renal injury in terms of urinary albumin excretion varies between summer and winter as well.
- Yi Cheng
- Chang-Sheng Sheng
- Ji-Guang Wang
Article14 Feb 2023 Hypertension Research
Area of residence and hypertension risk: need more evidence from low- and middle-income countries
- Rajat Das Gupta
Comment7 Apr 2023 Hypertension Research
Fat mass: the most sensitive predictor of persistent hypertension in unilateral primary aldosteronism
- Yuichi Yoshida
- Hirotaka Shibata
Comment10 Apr 2023 Hypertension Research
Effects of Uric Acid-Lowering Therapy on the Kidney (HTR-2023-0096.R2)
- Shun-ichiro Tsukamoto
- Hiromichi Wakui
- Kouichi Tamura
Comment8 Mar 2023 Hypertension Research
Preface–Metabolic aspects of hypertension in Asia
- Masaki Mogi
- Satoshi Hoshide
- Kazuomi Kario
Editorial8 May 2023 Hypertension Research
Real-world evidence of the association between blood pressure elevation and coronary artery disease and stroke in Japan
- Hisashi Kai
Editorial5 Jan 2023 Hypertension Research
Current status of the rapid decline in renal function due to diabetes mellitus and its associated factors: analysis using the National Database of Health Checkups in Japan
- Makoto Fujii
- Yuko Ohno
- Mai Kabayama
ArticleOpen Access2 Feb 2023 Hypertension Research
A higher resting heart rate is associated with cardiovascular event risk in patients with type 2 diabetes mellitus without known cardiovascular disease

High resting heart rate (RHR), particularly ≥70 bpm, was associated with the risk of cardiovascular events compared to RHR 60-69 bpm in patients with type 2 diabetes mellitus (T2DM), diabetic retinopathy, and hyperlipidemia, but without known cardiovascular disease.
- Shota Ikeda
- Keisuke Shinohara
- Hiroyuki Tsutsui
Article27 Jan 2023 Hypertension Research
Obesity indicators as mediators of the association between age at menopause and blood pressure values

We demonstrated obesity indicators showed significant mediating effects on the association between later age at menopause (≥50 years) and higher BP.
- Yong-Jun Wu
- Chao-Qiang Jiang
- Wei-Sen Zhang
Article26 Jan 2023 Hypertension Research
Metabolic dysfunction-associated fatty liver disease is associated with an increase in systolic blood pressure over time: linear mixed-effects model analyses

The presence of metabolic dysfunction-associated fatty liver disease (MAFLD) is significantly associated with an increase in systolic blood pressure over time.
- Kazuma Mori
- Marenao Tanaka
- Masato Furuhashi
Article30 Jan 2023 Hypertension Research
Serum triglyceride levels and incidence of hypertension in a general Japanese population: ISSA-CKD study

Casual serum triglyceride levels and incidence of hypertension in a general Japanese population: ISSA-CKD study.
- Shintaro Ishida
- Seiji Kondo
- Hisatomi Arima
Article24 Jan 2023 Hypertension Research
Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism

A significant effect of the interaction between plasma aldosterone concentration and the visceral-to-subcutaneous fat ratio on the tissue Doppler-derived E/e' ratio in patients with primary aldosteronism.
- Tatsuya Haze
- Moe Ozawa
- Nobuhito Hirawa
Article8 Feb 2023 Hypertension Research
Trends in blood pressure and hypertension among older adults and oldest-old individuals in China between 2008-2018
- Siyue Tan
- Dong Liu
- Hui Zuo
Article7 Feb 2023 Hypertension Research
New insights regarding clinical goals for preventing rapid decline in renal function in Japanese population
- Kensei Taguchi
- Kei Fukami
Comment21 Feb 2023 Hypertension Research
Resting heart rate as a possible biomarker and target to prevent future cardiovascular disease in type 2 diabetes patients (HTR-2023-0066.R2)
- Daisuke Kamimura
- Kouichi Tamura
Comment8 Mar 2023 Hypertension Research
Late age at menopause positively associated with obesity-mediated hypertension
- Satoshi Morimoto
- Atsuhiro Ichihara
Comment28 Feb 2023 Hypertension Research
Metabolic dysfunction-associated fatty liver disease reflects a significantly higher risk of hypertension than non-alcoholic fatty liver disease
- Tatsuki Uehara
- Hiromichi Wakui
- Kouichi Tamura
Comment3 Mar 2023 Hypertension Research
Visceral fat: a bad companion for mineralocorticoid receptor overactivation
- Yuichi Yoshida
- Hirotaka Shibata
Comment1 Mar 2023 Hypertension Research
The importance of lifestyle modification for hypertension in Asia
- Satoshi Hoshide
- Masaki Mogi
- Kazuomi Kario
Editorial5 Apr 2023 Hypertension Research
Blood pressure in heart failure management and prevention

Comparison between patients with and without heart failure regarding blood pressure The association between CV events and SBP is linear in patients without heart failure; however, it becomes J-shaped or inverse linear in those with heart failure. The management of BP, including optimal BP or pharmacotherapy, differs between the two populations. ACEi angiotensin-converting enzyme inhibitors, ARB angiotensin II receptor blockers; ARNi angiotensin receptor-neprilysin inhibitors, BB beta-blockers, BP blood pressure, CV cardiovascular, DASH Dietary Approaches to Stop Hypertension, GDMT guideline-directed medical therapy, HF heart failure, HFrEF heart failure with reduced ejection fraction, MRA mineralocorticoid receptor antagonists, SBP systolic blood pressure, SGLT2i sodium-glucose cotransporter 2 inhibitors.
- Daichi Maeda
- Taishi Dotare
- Tohru Minamino
Review Article5 Jan 2023 Hypertension Research
Secondhand smoke exposure is associated with the risk of hypertensive disorders of pregnancy: the Japan Environment and Children’s Study

The association between second-hand smoking exposure and hypertensive disorders of pregnancy risk was analyzed using the JECS data. The relative risks in 4–7 days/week and ≥2 h/day of SHS exposures were 1.18 and 1.27, respectively. The PAFs due to SHS exposure and maternal smoking were 3.80% and 1.81%, respectively.
- Kosuke Tanaka
- Hidekazu Nishigori
- and the Japan Environment and Children’s Study Group
ArticleOpen Access3 Feb 2023 Hypertension Research
Association between hypertension and myosteatosis evaluated by abdominal computed tomography

Advanced myosteatosis measured by abdominal CT taken at the L3 level was significantly correlated with a higher risk of hypertension even after adjusting for health behaviors, intake of lipid-lowering drugs, plasma lipid levels, and other ectopic fat distribution.
- Han Na Jung
- Yun Kyung Cho
- Chang Hee Jung
Article12 Jan 2023 Hypertension Research
The association of BP with cardiovascular outcomes in patients with dipstick proteinuria and preserved kidney function
- Yuta Suzuki
- Hidehiro Kaneko
- Issei Komuro
Article19 Jan 2023 Hypertension Research
Endothelial function, arterial stiffness and Framingham risk score in chronic kidney disease: A prospective observational cohort study
- Yisha Li
- Xinru Guo
- Guangyan Cai
Article11 Jan 2023 Hypertension Research
Fatty liver index predicts the development of hypertension in a Japanese general population with and without dysglycemia
- Dan Wu
- Aya Hirata
- Tomonori Okamura
Article11 Jan 2023 Hypertension Research
The impacts of secondhand smoke on future generations and the responsibility of society as a whole to protect the well-being of our future descendants
- Chisa Matsumoto
Comment8 Feb 2023 Hypertension Research
Which blood pressure threshold indicates a therapeutic benefit for patients with chronic kidney disease?
- Panagiotis I. Georgianos
- Evangelos Papachristou
- Vassilios Liakopoulos
Comment19 Jan 2023 Hypertension Research
Era of biomarker-based disease risk management
- Yukihito Higashi
Comment20 Jan 2023 Hypertension Research
Fatty liver index has potential as a predictor of hypertension in the Japanese general population
- Naoki Nakagawa
Comment7 Feb 2023 Hypertension Research
Lifetime home BP-centered approach is the core from onset to aggravation of hypertension
- Kazuomi Kario
- Satoshi Hoshide
- Masaki Mogi
Editorial31 Jan 2023 Hypertension Research
Relationship between the urinary Na/K ratio, diet and hypertension among community-dwelling older adults
- Noriko Yamanaka
- Mitsuyo Itabashi
- Takashi Takei
Article16 Dec 2022 Hypertension Research
Impact of continued high blood pressure on the progression of diabetic nephropathy after 10 years: KAMOGAWA-HBP study

We demonstrated that chronic home blood pressure was associated with the progression of diabetic nephropathy.
- Shinnosuke Hata
- Emi Ushigome
- Michiaki Fukui
Article11 Jan 2023 Hypertension Research
Blood pressure per the 2017 ACC/AHA and 2018 ESC/ESH guidelines and heart failure risk: the Suita Study
- Ahmed Arafa
- Yoshihiro Kokubo
- Chisato Izumi
Article6 Jan 2023 Hypertension Research
New 2019 JSH guidelines and the risk of incident cardiovascular disease: The Suita Study
- Ahmed Arafa
- Rena Kashima
- Yoshihiro Kokubo
Brief Communication23 Dec 2022 Hypertension Research
Target organ damage for the management of hypertension in the Asian population
- Satoshi Hoshide
- Masaki Mogi
- Kazuomi Kario
Editorial5 Jan 2023 Hypertension Research
Nephrons, podocytes and chronic kidney disease: Strategic antihypertensive therapy for renoprotection
- Kotaro Haruhara
- Go Kanzaki
- Nobuo Tsuboi
Review ArticleOpen Access12 Oct 2022 Hypertension Research
Impact of hypertension and diabetes on the onset of chronic kidney disease in a general Japanese population

Impact of hypertension and diabetes on the onset of chronic kidney disease in a general Japanese population.
- Akira Kaneyama
- Aya Hirata
- Tomonori Okamura
Article28 Sep 2022 Hypertension Research
Association of rate pressure product trajectories at an early age with left ventricular hypertrophy in midlife: a prospective cohort study

Study summary. LVH left ventricular hypertrophy, CA carotid atherosclerosis, SRD subclinical renal damage, TOD target organ damage.
- Wenling Zheng
- Jianjun Mu
- Dan Luo
Article24 Oct 2022 Hypertension Research
The association between inflammatory biomarkers and carotid artery plaque in normal-weight and metabolically healthy Chinese adults: a cross-sectional study
- Xiaomin Zhang
- Ting Zhang
- Renying Xu
Article12 Oct 2022 Hypertension Research
The public health impact of hypertension and diabetes: a powerful tag team for the development of chronic kidney disease
- Kentaro Kohagura
Comment6 Dec 2022 Hypertension Research
Left ventricular hypertrophy was not built in a day
- Keisuke Kida
Comment2 Dec 2022 Hypertension Research
Preface—this month’s Asian perspectives
- Masaki Mogi
- Satoshi Hoshide
- Kazuomi Kario
Editorial6 Feb 2023 Hypertension Research
Association of serum uric acid with the risk of developing hypertension: A prospective cohort study with mediation analysis
- Jing Dong
- Li-Kun Hu
- Yu-Xiang Yan
Article10 Nov 2022 Hypertension Research
Concept, study design, and baseline blood pressure control status of the nationwide prospective HI–JAMP study using multisensor ABPM

Concept and device of the HI–JAMP study using new ICT-based multisensor ABPM. BP blood pressure, ABPM ambulatory blood pressure monitoring
- Kazuomi Kario
- Naoko Tomitani
- Satoshi Hoshide
Article15 Nov 2022 Hypertension Research
Association of blood pressure and hypertension between parents and offspring: The Korea National Health and Nutrition Examination Survey

We investigated the familial association of hypertension between offspring and their parents in South Korea. The prevalence of hypertension in boys and girls tended to increase based on the number of parents with hypertension. The risk of having hypertension among offspring was approximately two times higher when one parent was hypertensive and over four times higher when both parents were hypertensive compared to controls whose parents were not hypertensive. OR odds ratio, HTN hypertension, BP blood pressure.
- Seoyun Jang
- Susan Taejung Kim
- Young Hwan Song
ArticleOpen Access2 Dec 2022 Hypertension Research
Association of first trimester serum uric acid with preeclampsia: an observational cohort study with propensity score matching

Elevated serum uric acid levels before 20 weeks of gestation are associated with the development of preeclampsia, especially in the early 8–12 weeks of gestation, and the effect attenuates with increasing gestational weeks, which suggest that elevated uric acid in early pregnancy may be a causative factor in preeclampsia.
- Chaoyan Yue
- Chunmei Ying
- Xiaotian Li
Article20 Dec 2022 Hypertension Research
Uncontrolled hypertension: the greatest challenge and perspectives in Asia
- Kazuomi Kario
- Satoshi Hoshide
- Masaki Mogi
Editorial5 Dec 2022 Hypertension Research
Investigation of the urinary sodium-to-potassium ratio target level based on the recommended dietary intake goals for the Japanese population: The INTERMAP Japan

Our proposition is accomplishing cutoff value of approximately 2 for urinary Na/K ratio would be desirable to meet the DRIs dietary goals of both Na and K simultaneously in middle-aged Japanese men and women accustomed to Japanese dietary habits.
- Ebtehal Salman
- Aya Kadota
- for the INTERMAP Research Group
ArticleOpen Access8 Nov 2022 Hypertension Research
Insufficient blood pressure control is independently associated with increased arterial stiffness
- Takeko Kawabata
- Takuro Kubozono
- Mitsuru Ohishi
Article4 Oct 2022 Hypertension Research
Increased risk of metastasis in patients with incidental use of renin-angiotensin system inhibitors: a retrospective analysis for multiple types of cancer based on electronic medical records
- Akie Hirata
- Shin Ishikane
- Naoki Nakashima
Article28 Sep 2022 Hypertension Research
Clinical impact of blood pressure on cardiovascular death in patients 80 years and older following acute myocardial infarction: a prospective cohort study
- Meng Zhang
- Xiao-Ni Yan
- Jian-Jun Li
Article20 Sep 2022 Hypertension Research
High-normal diastolic blood pressure as a risk factor for left ventricular diastolic dysfunction in healthy postmenopausal women
- Makiko Kimura
- Haruki Sekiguchi
- Junich Yamaguchi
Article6 Oct 2022 Hypertension Research
The eighth installment in Asian perspectives, salt, pregnancy, and masked hypertension
- Masaki Mogi
- Satoshi Hoshide
- Kazuomi Kario
Editorial7 Nov 2022 Hypertension Research
Exponential increase of the gestational-age-specific incidence of preeclampsia onset (COPE study): a multicenter retrospective cohort study in women with maternal check-ups at <20 weeks of gestation in Japan
- Akihide Ohkuchi
- Hirotada Suzuki
- Shigeru Saito
Article15 Sep 2022 Hypertension Research
The prevalence of masked hypertension and masked uncontrolled hypertension in relation to overweight and obesity in a nationwide registry in China

Our study showed that overweight and obesity were associated with a higher prevalence of masked uncontrolled hypertension but not masked hypertension, indicating that clinic blood pressure might overestimate antihypertensive treatment effects in patients with overweight and obesity.
- Jia-Hui Xia
- Dong-Yan Zhang
- Ji-Guang Wang
Article14 Sep 2022 Hypertension Research
The next stage of hypertension management in Asia
- Satoshi Hoshide
- Masaki Mogi
- Kazuomi Kario
Editorial5 Oct 2022 Hypertension Research
Reduced masticatory performance and not using dentures are associated with hypertension in older adults with tooth loss: the Shimane CoHRE study
- Takafumi Abe
- Kazumichi Tominaga
- Toru Nabika
Article22 Jul 2022 Hypertension Research
A multicenter prospective study of home blood pressure measurement (HBPM) during pregnancy in Japanese women

The hypertensive cut-off in HBP by HBPM was determined in Japanese pregnant women. (A) Optimizing the polynomial of systolic HBP that induces the hypertensive boundary value by HBPM. By the polynomial equation of mean +3 SD, systolic HBP at 35 weeks gestation equal to non-pregnant was 135 mmHg, the current reference value for non-pregnant hypertension of HBPM. Polynomial of mean +3 SD was considered optimal. (B) Optimization of polynomial of diastolic HBP that induces the hypertensive boundary value by HBPM. By polynomial of mean +2SD, diastolic HBP at 38 weeks gestation equal to non-pregnant was 85 mmHg, the current standard for non-pregnant hypertension by HBPM. Thus, polynomial of mean +2 SD was considered optimal.
- Yoshikatsu Suzuki
- Keiichi Matsubara
- Shigeru Saito
Article16 Aug 2022 Hypertension Research
Effect of COVID-19 pandemic on seasonal cardiovascular mortality in Japan, and Asian evidence
- Kazuomi Kario
- Masaki Mogi
- Satoshi Hoshide
Editorial5 Sep 2022 Hypertension Research
Time-series analysis of blood pressure changes after the guideline update in 2019 and the coronavirus disease pandemic in 2020 using Japanese longitudinal data
- Michihiro Satoh
- Takahisa Murakami
- Hirohito Metoki
Article20 Jun 2022 Hypertension Research
Prevalence and clinical characteristics of primary aldosteronism in a tertiary-care center in Korea

(A) The prevalence of PA was 6.1% of the total population. Among 55 patients with conclusive subtype differentiation of PA, 27% had APA, 65% had BAH, and 7% had UAH. (B) Patients with PA had a higher blood pressure and higher prevalence of target-organ damage than patients without PA. APA, aldosterone-producing adenoma; BAH, bilateral adrenal hyperplasia; ECG, electrocardiogram; LVH, left ventricular hypertrophy; PA, primary aldosteronism; SBP, systolic blood pressure; UAH, unilateral adrenal hyperplasia.
- Minjae Yoon
- Namki Hong
- Sungha Park
Article9 Jun 2022 Hypertension Research
Transportation physical activity and new-onset hypertension: A nationwide cohort study in China

Moderate transportation PA is associated with a lower risk of new-onset hypertension among Chinese adults.
- Rui Li
- Shaojie Zhang
- Xianhui Qin
Article13 Jul 2022 Hypertension Research
Antihypertensive drug prescription trends for pregnant women with hypertension in acute hospitals in Japan
- Daisuke Kikuchi
- Taku Obara
- Kouji Okada
Brief Communication17 Jun 2022 Hypertension Research
The fifth story in Asian perspectives, regions, new markers, and renal denervation
- Masaki Mogi
- Satoshi Hoshide
- Kazuomi Kario
Editorial5 Aug 2022 Hypertension Research
Prevalence of hypertension and its relationship with altitude in highland areas: a systematic review and meta-analysis
- Xin Zhang
- Zhipeng Zhang
- Xiaoping Chen
Review Article15 Jun 2022 Hypertension Research
Left ventricular mass as a predictor of cardiovascular events in the era of hypertension management using home blood pressure measurement: the J-HOP study
- Hirotaka Waki
- Satoshi Hoshide
- Kazuomi Kario
Article13 May 2022 Hypertension Research
The independent association between salivary alpha-amylase activity and arterial stiffness in Japanese men and women: the Toon Health Study
- Tomokazu Tajima
- Ai Ikeda
- Takeshi Tanigawa
Article22 Jun 2022 Hypertension Research
Association between social participation and hypertension control among older people with self-reported hypertension in Japanese communities

Association of the social participation with hypertension control among older people with hypertension.
- Takayuki Ueno
- Atsushi Nakagomi
- Katsunori Kondo
Brief Communication15 Jun 2022 Hypertension Research
Prognostic value of target organ damage in patients with cardiovascular risks
- Naoki Nakagawa
Comment3 Jun 2022 Hypertension Research
Patient preference and Long-term outcome of renal denervation for resistant hypertension
- Yukako Ogoyama
- Kazuomi Kario
Comment9 Jun 2022 Hypertension Research
A Commentary to “The prevalence of hypertensive diseases and treated hypertensive patients in Japan: a nationwide administrative claims database study”
- Sungha Park
Comment10 Jun 2022 Hypertension Research
Current status of hypertension and treatment in Asia
- Satoshi Hoshide
- Masaki Mogi
- Kazuomi Kario
Editorial5 Jul 2022 Hypertension Research
Angiotensin receptor–neprilysin inhibitors for hypertension—hemodynamic effects and relevance to hypertensive heart disease

Potential mechanisms contributing to the effects of angiotensin receptor–neprilysin inhibitors (ARNIs) on 24-h blood pressure and hypertensive heart disease. CV, cardiovascular; LV, left ventricular.
- Kazuomi Kario
- Bryan Williams
Review Article2 May 2022 Hypertension Research
2022 Malaysian Working Group Consensus Statement on Renal Denervation for management of arterial hypertension
- Yook Chin Chia
- Wan Azman Wan Ahmad
- Tiong Kiam Ong
ArticleOpen Access1 Jun 2022 Hypertension Research
Prevalence of hypertensive diseases and treated hypertensive patients in Japan: A nationwide administrative claims database study

27 million Japanese are hypertensive disease and 89.6% of them are treated with any anti-hypertensive medications. This is the first study utilizing the National Database of Health Insurance Claims and Specific Health Checkups to determine the number and age-adjusted prevalence of hypertensive patients and treated hypertensive patients in Japan.
- Takashi Waki
- Katsuyuki Miura
- Naohiro Mitsutake
Article10 Jun 2022 Hypertension Research
Plasma B-type natriuretic peptide level as a possible predictor of dietary salt intake
- Yasuaki Dohi
Comment18 May 2022 Hypertension Research
Long-term blood pressure lowering effect of renal denervation and its patient preference, salt intake, and stroke in Asia
- Kazuomi Kario
- Satoshi Hoshide
- Masaki Mogi
Editorial6 Jun 2022 Hypertension Research
Blood pressure management for secondary stroke prevention

Hypertension shows a direct and indirect association with all stroke subtypes; the strongest association is observed between hypertension and SVD (which predisposes to LI and ICH), a modest association is observed with LAA, and an indirect association with NVAF and the development and enlargement of cerebral aneurysms. Direct and indirect association between hypertension and etiology of all stroke subtypes would underline the closest association between stroke and hypertension among vascular risk factors and explain the importance of blood pressure management for secondary stroke prevention.
- Kazuo Kitagawa
Review Article18 Apr 2022 Hypertension Research
Positive relationships between annual changes in salt intake and plasma B-type natriuretic peptide levels in the general population without hypertension and heart diseases

We recruited 3051 participants without hypertension and heart diseases for two consecutive years. Participants in the highest quartile of annual changes in daily salt intake showed the largest annual changes in plasma BNP. We concluded that annual changes in plasma BNP indicated a significant positive association with daily salt intake.
- Naro Ohashi
- Hiroyuki Takase
- Hideo Yasuda
Article14 Apr 2022 Hypertension Research
Patient preference for renal denervation therapy in hypertension: A cross-sectional survey in Chengdu, China
- Zhipeng Zhang
- Xin Zhang
- Xiaoping Chen
Article6 Apr 2022 Hypertension Research
Long-term outcome of renal nerve denervation (RDN) for resistant hypertension

Heterogenous BP responses after RDN for resistant hypertension. The bar graph represents the difference in SBP at 6 months after RDN compared with the baseline SBP, for each patient (1A). Efficacy of the renal denervation procedure. Percentage of patients whose SBP decreased ≥10 mmHg from baseline or whose medication decreased from baseline (1B).
- Pariya Panchavinnin
- Sirisawat Wanthong
- Nattawut Wongpraparut
Brief CommunicationOpen Access7 Apr 2022 Hypertension Research
Preface—Special issue for hypertension in Asia: from the Okinawa declaration to the ISH 2022
- Satoshi Hoshide
- Akira Nishiyama
- Kazuomi Kario
Editorial5 Apr 2022 Hypertension Research
STEP to blood pressure management of elderly hypertension: evidence from Asia
- Wei-li Zhang
- Jun Cai
Review ArticleOpen Access11 Mar 2022 Hypertension Research
Controlling blood pressure soon after intracerebral hemorrhage: The SAMURAI-ICH Study and its successors
- Kazunori Toyoda
- Masatoshi Koga
- as the SAMURAI Investigators
Review ArticleOpen Access8 Mar 2022 Hypertension Research
Intensive or standard blood pressure control in patients with a history of ischemic stroke: RESPECT post hoc analysis

A total of 1074 patients with a history of ischemic stroke enrolled in The Recurrent Stroke Prevention Clinical Outcome (RESPECT) Study were assigned to intensive blood pressure (BP) control group (blood pressure < 120/80 mmHg) or standard blood pressure control group (blood pressure < 140/90 mmHg) and were followed up for a mean of 3.9 years. Seventy-eight first recurrent strokes occurred, including 70 ischemic stroke and 8 intracerebral hemorrhage. Intensive treatment did not change annual risk of ischemic stroke (1.74% vs. 1.75%, P = 0.999), but markedly reduced risk of hemorrhagic stroke (0.00% vs. 0.39%, P = 0.005). Beneficial effect of intensive BP control were observed for risk of hemorrhagic stroke in the patients with a history of ischemic stroke.
- Kazuo Kitagawa
- Hisatomi Arima
- for the Recurrent Stroke Prevention Clinical Outcome (RESPECT) Study Group
Article4 Mar 2022 Hypertension Research
Differential effect of a xanthine oxidase inhibitor on arterial stiffness and carotid atherosclerosis: a subanalysis of the PRIZE study

Xanthine oxidase (XO) inhibition by febuxostat, rather than the effect of lowering hyperuricemia, may have directly contributed to the improvement of arterial stiffness in the present study. Plausible explanations of this beneficial effect are proposed as the counter action via XO inhibition to macrophage adventitial infiltration, vascular cell hypertrophy, and proliferation of vascular smooth muscle cell and vascular wall connective tissues or endothelial dysfunction.
- Kazuki Shiina
- Hirofumi Tomiyama
- the PRIZE Study Investigators
Article15 Feb 2022 Hypertension Research
Preface–special issue on hypertension in Asia: the second story
- Masaki Mogi
- Satoshi Hoshide
- Kazuomi Kario
Editorial6 May 2022 Hypertension Research
Dietary salt intake in Japan - past, present, and future
- Takuya Tsuchihashi
Review Article16 Mar 2022 Hypertension Research
Diuretics versus others for long-term clinical outcomes as first-line antihypertensive medications: analysis of national real-world database

In a real-world Korean population without cardiovascular disease, the use of diuretics as firstline antihypertensive medication was not superior to other antihypertensive medications in terms of reducing long-term cardiovascular risk.
- Hack-Lyoung Kim
- Doyeon Hwang
- Ki-Chul Sung
Article25 Mar 2022 Hypertension Research
Intensive blood pressure lowering for ischemic stroke patients: does it prevent ischemia or bleeding?
- Kazunori Toyoda
CommentOpen Access22 Mar 2022 Hypertension Research
Uric acid, xanthine oxidase, and vascular damage: potential of xanthine oxidoreductase inhibitors to prevent cardiovascular diseases
- Hiromitsu Sekizuka
Comment17 Mar 2022 Hypertension Research
Latest hypertension research to inform clinical practice in Asia
- Kazuomi Kario
- Masaki Mogi
- Satoshi Hoshide
Editorial5 Apr 2022 Hypertension Research
Hypertension management to prevent dementia
- Masaki Mogi
Editorial5 Apr 2022 Hypertension Research
Clinical characteristics of older adults with hypertension and unrecognized cognitive impairment
- Koichi Yamamoto
- Hiroshi Akasaka
- Cherry Study Group
Article24 Feb 2022 Hypertension Research
Sociodemographic correlates of knowledge about high sodium-related diseases among adults in Malaysia

Income, educational level, gender, ethnicity, house locality and hypertension influenced the knowledge of high sodium-related diseases.
- Yong Kang Cheah
- Sharifah Nazeera Syed Anera
- Mohd Azahadi Omar
Article16 Feb 2022 Hypertension Research