Focus

Super–resolution imaging

Optical imaging beyond the diffraction limit of light is revolutionizing sample analysis in the biological and physical sciences. In this special Focus Issue, a collection of articles are presented, detailing the fundamental physics, the different approaches and the applications where super–resolution imaging can be of help.

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Editorial

Beyond the diffraction limit pp361

doi:10.1038/nphoton.2009.100


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Commentaries

Subdiffraction resolution in continuous samples pp362 - 364

Rainer Heintzmann & Mats G. L. Gustafsson

doi:10.1038/nphoton.2009.102

Super-resolution light microscopy methods either localize single molecular labels or treat the sample as a continuous object. The fundamental requirements for super-resolution in the continuum regime are spatially non-uniform illumination and a nonlinear photoresponse.

Nano–imaging with STORM pp365 - 367

Xiaowei Zhuang

doi:10.1038/nphoton.2009.101

Multicolour, three-dimensional stochastic optical reconstruction microscopy now makes it possible to image cellular structures with near molecular-scale resolution.


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Interview

Eyes on super-resolution pp368 - 369

Interview with W. E. Moerner

doi:10.1038/nphoton.2009.103

Advanced imaging techniques have evolved to see beyond the diffraction limit. W. E. Moerner spoke to Nature Photonics about the techniques involved.


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Progress Article

Diffraction-unlimited three-dimensional optical nanoscopy with opposing lenses pp381 - 387

Stefan W. Hell, Roman Schmidt & Alexander Egner

doi:10.1038/nphoton.2009.112


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Review

Plasmonics for near-field nano-imaging and superlensing  pp388 - 394

Satoshi Kawata, Yasushi Inouye & Prabhat Verma

doi:10.1038/nphoton.2009.111


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