Neural organoids

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Stem cells are known to be capable to differentiate into specialized cells, even under in-vitro settings, and to form 3D organ-like structures in a dish, often referred to as organoids. Neural organoids derived from induced pluripotent stem cells offer great potential to study human neurons, neuron-glia interactions and different neuronal cell types that form complex neuronal networks, and to elucidate mechanisms of CNS function and dysfunction.

For this Collection, we encourage submissions that highlight recent advances in the biology of neural organoids and how neural organoids could be utilized to study the mechanisms of neural networks and dysfunction in neuropsychiatric conditions. Alongside original Research Articles, we will also consider Reviews, Perspectives and Comments covering these topics. All submissions will be subject to the same review process as regular Communications Biology Articles and all studies, especially those using human-derived organoids, should have all appropriate and relevant ethical approval and practices in place.

Abstract image of pink and white diagonal neurons over blue background with nervous cells. Concept of science and medicine. 3d rendering double exposure.