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Adult neurogenesis supports important brain functions, such as learning and memory, and its sharp decrease during aging may contribute to the cognitive decline of the aged brain. This Collection aims to gain insight into the cellular and molecular drivers of the age-associated reduction of adult neurogenesis, by gathering studies investigating the mechanisms of neurogenic aging in rodents and other vertebrate and invertebrate model systems, employing both in vivo and in vitro approaches.
Adult neurogenesis supports important brain functions, such as learning and memory, and its decrease during aging may contribute to the cognitive decline of the aged brain. This Collection provides insight into the role, regulation, and age-associated reduction of adult neurogenesis, by gathering studies investigating this process in different model systems, ages, and brain regions.