Collection 

Cryo-electron microscopy

Submission status
Closed
Submission deadline

The first light microscope is thought to have been produced in the early 16th century. Of course it was much simpler than what is now available, however, as imaging technology has improved, resolution is no longer limited by the microscope, but by the wavelength of light itself; a different source of illumination is needed. Electron microscopes use a beam of electrons in place of light, and are therefore able to produce much higher resolution images. However, in order to visualise biomolecules directly (without burning them up), samples must be frozen and a gentler electron beam used: cryo-electron microscopy. Following a number of breakthroughs in the associated hardware and software over the last ten years, we have seen an explosion in the number of protein structures being determined by cryo-electron microscopy, and its application to studying larger structures – macromolecules, viruses, cells – has become much more widely mainstream.

This Collection invites original research presenting structures derived from cryo-EM as well as contributions to the underlying methods and technology.

Macrophage, TEM - stock photo

Editors

Submitting a paper for consideration

 

To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Cryo-electron microscopy" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.

Accepted papers are published on a rolling basis as soon as they are ready.

In addition to papers on Cryo-electron microscopy, Scientific Reports welcomes all original research in Structural biology. To browse our latest articles in Structural biology click here.

 

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