The human genome at 20

The past two decades have witnessed extraordinary technological and computational advances in nucleic acid sequencing.This Milestone timeline provides a perspective of major genomic sequencing-related developments in the 21st century.

By re-committing to data sharing, researchers can fulfil the long-delayed promise of the Human Genome Project.

Data sharing was a core principle that led to the success of the Human Genome Project 20 years ago. Now scientists are struggling to keep information free.

A new analysis traces the story of the draft genome’s impact on genomics since 2001, linking its effects on publications, drug approvals and understanding of disease.

Capture the full scope of variation to improve health care, equity and medical research globally.

Looking back at the publication of the human genome, and how macrophages mend muscle.

Since the human genome was published in 2001, many of the gaps in the original sequence have been filled in, offering a more detailed understanding of genome regulation, structure and function.

Mendelian diseases are caused by mutations in a single gene. The first draft of the human genome, published in 2001, had broad implications for how these diseases are diagnosed, managed and prevented.

In the 20 years since the first drafts of the human genome were made public, an explosion in genome sequencing has revealed how our evolutionary history and health can be understood by analysing the diversity in our genomes.