Editor’s choice: World Cancer Day

Cancer is a leading cause of death worldwide. Each year, roughly 10 million people die of cancer – more than HIV/AIDs, malaria, and tuberculosis combined. Nearly a third of these deaths could be prevented by early detection and treatment. Meanwhile, up to half of all cancers can be prevented altogether by reducing modifiable risk factors like diet, tobacco and alcohol use, and exercise. Differences in access to cancer care, including prevention, diagnosis, and treatment, exist both across and within countries. This healthcare equity gap leads to worse outcomes and disproportionate mortality in low- and middle-income countries and among racial and ethnic minority groups. Nevertheless, cancer research – basic, clinical, and epidemiological – is advancing our understanding of this disease and improving our ability to prevent, detect, and treat it. In recognition of World Cancer Day, this Collection highlights recent examples of this critical research.