Scientific Reports

Collection 10 March 2022

Top 100 in Neuroscience

This collection highlights our most downloaded* neuroscience papers published in 2021. Featuring authors from around the world, these papers showcase valuable research from an international community.

*Data obtained from SN Inights, which is based on Digital Science's Dimensions.

1-25

Musical components important for the Mozart K448 effect in epilepsy
- Robert J. Quon
- Michael A. Casey
- Barbara C. Jobst
ArticleOpen Access16 Sep 2021 Scientific Reports
Brain structure changes associated with sexual orientation
- Mikhail Votinov
- Katharina S. Goerlich
- Ute Habel
ArticleOpen Access3 Mar 2021 Scientific Reports
Selective time-dependent changes in activity and cell-specific gene expression in human postmortem brain
- Fabien Dachet
- James B. Brown
- Jeffrey A. Loeb
ArticleOpen Access23 Mar 2021 Scientific Reports
Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition
- Lisa Mosconi
- Valentina Berti
- Roberta Diaz Brinton
ArticleOpen Access9 Jun 2021 Scientific Reports
Multimodal deep learning models for early detection of Alzheimer’s disease stage
- Janani Venugopalan
- Li Tong
- May D. Wang
ArticleOpen Access5 Feb 2021 Scientific Reports
Brain tumor segmentation based on deep learning and an attention mechanism using MRI multi-modalities brain images
- Ramin Ranjbarzadeh
- Abbas Bagherian Kasgari
- Malika Bendechache
ArticleOpen Access25 May 2021 Scientific Reports
Splitting sleep between the night and a daytime nap reduces homeostatic sleep pressure and enhances long-term memory
- James N. Cousins
- Ruth L. F. Leong
- Michael W. L. Chee
ArticleOpen Access5 Mar 2021 Scientific Reports
Listening to speech with a guinea pig-to-human brain-to-brain interface
- Claus-Peter Richter
- Petrina La Faire
- Alan G. Micco
ArticleOpen Access10 Jun 2021 Scientific Reports
Benefit of human moderate running boosting mood and executive function coinciding with bilateral prefrontal activation
- Chorphaka Damrongthai
- Ryuta Kuwamizu
- Hideaki Soya
ArticleOpen Access22 Nov 2021 Scientific Reports
Enhanced activations in syntax-related regions for multilinguals while acquiring a new language
- Keita Umejima
- Suzanne Flynn
- Kuniyoshi L. Sakai
ArticleOpen Access31 Mar 2021 Scientific Reports
Brain-inspired spiking neural networks for decoding and understanding muscle activity and kinematics from electroencephalography signals during hand movements
- Kaushalya Kumarasinghe
- Nikola Kasabov
- Denise Taylor
ArticleOpen Access28 Jan 2021 Scientific Reports
Longitudinal effects of meditation on brain resting-state functional connectivity
- Zongpai Zhang
- Wen-Ming Luh
- Weiying Dai
ArticleOpen Access31 May 2021 Scientific Reports
Evidence of a new hidden neural network into deep fasciae
- Caterina Fede
- Lucia Petrelli
- Carla Stecco
ArticleOpen Access16 Jun 2021 Scientific Reports
Cross-sex hormone treatment and own-body perception: behavioral and brain connectivity profiles
- Behzad S. Khorashad
- Amirhossein Manzouri
- Ivanka Savic
ArticleOpen Access2 Feb 2021 Scientific Reports
A directional 3D neurite outgrowth model for studying motor axon biology and disease
- Xandor M. Spijkers
- Svetlana Pasteuning-Vuhman
- R. Jeroen Pasterkamp
ArticleOpen Access22 Jan 2021 Scientific Reports
The role of dorsolateral and ventromedial prefrontal cortex in the processing of emotional dimensions
- Vahid Nejati
- Reyhaneh Majdi
- Michael A. Nitsche
ArticleOpen Access21 Jan 2021 Scientific Reports
How neurons exploit fractal geometry to optimize their network connectivity
- Julian H. Smith
- Conor Rowland
- R. P. Taylor
ArticleOpen Access27 Jan 2021 Scientific Reports
Defining early changes in Alzheimer’s disease from RNA sequencing of brain regions differentially affected by pathology
- Boris Guennewig
- Julia Lim
- Greg T. Sutherland
ArticleOpen Access1 Mar 2021 Scientific Reports
Narcissistic personality traits and prefrontal brain structure
- Igor Nenadić
- Carsten Lorenz
- Christian Gaser
ArticleOpen Access3 Aug 2021 Scientific Reports
EEG-based diagnostics of the auditory system using cochlear implant electrodes as sensors
- Ben Somers
- Christopher J. Long
- Tom Francart
ArticleOpen Access8 Mar 2021 Scientific Reports
Investigating real-life emotions in romantic couples: a mobile EEG study
- Julian Packheiser
- Gesa Berretz
- Sebastian Ocklenburg
ArticleOpen Access13 Jan 2021 Scientific Reports
Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice
- Kauê Machado Costa
- Daniela Schenkel
- Jochen Roeper
ArticleOpen Access8 Feb 2021 Scientific Reports
Functional network connectivity during Jazz improvisation
- Victor M. Vergara
- Martin Norgaard
- Vince D. Calhoun
ArticleOpen Access24 Sep 2021 Scientific Reports
Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice
- Jeon-Kyung Kim
- Sang-Kap Han
- Dong-Hyun Kim
ArticleOpen Access17 Mar 2021 Scientific Reports
Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease
- Bradley R. Groveman
- Natalia C. Ferreira
- Cathryn L. Haigh
ArticleOpen Access9 Mar 2021 Scientific Reports

26-50

Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model
- Jisu Shin
- Sohui Park
- YoungSoo Kim
ArticleOpen Access15 Jan 2021 Scientific Reports
Ambulatory seizure forecasting with a wrist-worn device using long-short term memory deep learning
- Mona Nasseri
- Tal Pal Attia
- Benjamin H. Brinkmann
ArticleOpen Access9 Nov 2021 Scientific Reports
Post-traumatic seizures and antiepileptic therapy as predictors of the functional outcome in patients with traumatic brain injury
- Valeria Pingue
- Chiara Mele
- Antonio Nardone
ArticleOpen Access25 Feb 2021 Scientific Reports
Human α-synuclein overexpression in a mouse model of Parkinson’s disease leads to vascular pathology, blood brain barrier leakage and pericyte activation
- Osama Elabi
- Abderahim Gaceb
- Gesine Paul
ArticleOpen Access13 Jan 2021 Scientific Reports
Neuropsychiatric profiles and conversion to dementia in mild cognitive impairment, a latent class analysis
- Natalia Roberto
- Maria J. Portella
- Sergi Valero
ArticleOpen Access19 Mar 2021 Scientific Reports
Comparative neuroanatomy of the lumbosacral spinal cord of the rat, cat, pig, monkey, and human
- Amirali Toossi
- Bradley Bergin
- Vivian K. Mushahwar
ArticleOpen Access21 Jan 2021 Scientific Reports
A personalized and evolutionary algorithm for interpretable EEG epilepsy seizure prediction
- Mauro. F. Pinto
- Adriana Leal
- César A. Teixeira
ArticleOpen Access9 Feb 2021 Scientific Reports
The effects of positive or negative self-talk on the alteration of brain functional connectivity by performing cognitive tasks
- Junhyung Kim
- Joon Hee Kwon
- Jae-Jin Kim
ArticleOpen Access21 Jul 2021 Scientific Reports
Deep learning-Based 3D inpainting of brain MR images
- Seung Kwan Kang
- Seong A. Shin
- Jae Sung Lee
ArticleOpen Access18 Jan 2021 Scientific Reports
Both high fat and high carbohydrate diets impair vagus nerve signaling of satiety
- Hailley Loper
- Monique Leinen
- Matthew A. Schiefer
ArticleOpen Access17 May 2021 Scientific Reports
PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons
- Sarah J. Brown
- Ibrahim Boussaad
- Oliver Bandmann
ArticleOpen Access23 Mar 2021 Scientific Reports
Altered spontaneous activity in the frontal gyrus in dry eye: a resting-state functional MRI study
- Kang Yu
- Yu Guo
- Yi Shao
ArticleOpen Access21 Jun 2021 Scientific Reports
Online and offline effects of transcranial alternating current stimulation of the primary motor cortex
- Ivan Pozdniakov
- Alicia Nunez Vorobiova
- Matteo Feurra
ArticleOpen Access16 Feb 2021 Scientific Reports
Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips
- H. H. T. Middelkamp
- A. H. A. Verboven
- A. D. van der Meer
ArticleOpen Access26 Jan 2021 Scientific Reports
Brain MRI in SARS-CoV-2 pneumonia patients with newly developed neurological manifestations suggestive of brain involvement
- Batil Alonazi
- Ahmed M. Farghaly
- Mustafa Z. Mahmoud
ArticleOpen Access14 Oct 2021 Scientific Reports
Diazepam causes sedative rather than anxiolytic effects in C57BL/6J mice
- Marina Pádua-Reis
- Diana Aline Nôga
- Martina Blunder
ArticleOpen Access29 Apr 2021 Scientific Reports
Photons detected in the active nerve by photographic technique
- Andrea Zangari
- Davide Micheli
- Maria Emiliana Caristo
ArticleOpen Access4 Feb 2021 Scientific Reports
Cannabidiol induces autophagy via ERK1/2 activation in neural cells
- Talita A. M. Vrechi
- Anderson H. F. F. Leão
- Gustavo J. S. Pereira
ArticleOpen Access8 Mar 2021 Scientific Reports
Deep learning-based pupil model predicts time and spectral dependent light responses
- Babak Zandi
- Tran Quoc Khanh
ArticleOpen Access12 Jan 2021 Scientific Reports
ATP signaling in the integrative neural center of Aplysia californica
- János Györi
- Andrea B. Kohn
- Leonid L. Moroz
ArticleOpen Access9 Mar 2021 Scientific Reports
EEG signals respond differently to idea generation, idea evolution and evaluation in a loosely controlled creativity experiment
- Wenjun Jia
- Yong Zeng
ArticleOpen Access22 Jan 2021 Scientific Reports
Cognitive and MRI trajectories for prediction of Alzheimer’s disease
- Samaneh A. Mofrad
- Astri J. Lundervold
- Alexander S. Lundervold
ArticleOpen Access22 Jan 2021 Scientific Reports
Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells
- Angela Duong
- Alesya Evstratova
- Ana C. Andreazza
ArticleOpen Access25 Feb 2021 Scientific Reports
Astrocytic expression of the Alzheimer’s disease risk allele, ApoEε4, potentiates neuronal tau pathology in multiple preclinical models
- Angela Marie Jablonski
- Lee Warren
- Bhavya Voleti
ArticleOpen Access9 Feb 2021 Scientific Reports
Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy
- Samantha T. Reyes
- Robert M. J. Deacon
- Frederick T. Chin
ArticleOpen Access25 Aug 2021 Scientific Reports

51-75

Magnetic domains oscillation in the brain with neurodegenerative disease
- Gunther Kletetschka
- Robert Bazala
- Eva Svecova
ArticleOpen Access12 Jan 2021 Scientific Reports
Right frontal anxiolytic-sensitive EEG ‘theta’ rhythm in the stop-signal task is a theory-based anxiety disorder biomarker
- Shabah M. Shadli
- Lynne C. Ando
- Neil McNaughton
ArticleOpen Access5 Oct 2021 Scientific Reports
Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation
- Debora Giunti
- Chiara Marini
- Antonio Uccelli
ArticleOpen Access18 Jan 2021 Scientific Reports
Position sensitive measurement of trace lithium in the brain with NIK (neutron-induced coincidence method) in suicide
- J. Schoepfer
- R. Gernhäuser
- M. Graw
ArticleOpen Access25 Mar 2021 Scientific Reports
Major oscillations in spontaneous home-cage activity in C57BL/6 mice housed under constant conditions
- Karin Pernold
- Eric Rullman
- Brun Ulfhake
ArticleOpen Access2 Mar 2021 Scientific Reports
Involvement of the dopaminergic system in the reward-related behavior of pregabalin
- Yusuf S. Althobaiti
- Farooq M. Almutairi
- Zahoor A. Shah
ArticleOpen Access19 May 2021 Scientific Reports
A high-density electroencephalography study reveals abnormal sleep homeostasis in patients with rapid eye movement sleep behavior disorder
- Amandine Valomon
- Brady A. Riedner
- Melanie Boly
ArticleOpen Access26 Feb 2021 Scientific Reports
MEG signatures of long-term effects of agreement and disagreement with the majority
- A. Gorin
- V. Klucharev
- A. Shestakova
ArticleOpen Access8 Feb 2021 Scientific Reports
Stroke prediction in patients presenting with isolated dizziness in the emergency department
- June-sung Kim
- Hong Jun Bae
- Won Young Kim
ArticleOpen Access17 Mar 2021 Scientific Reports
Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption
- Amy C. Reichelt
- Claire A. Lemieux
- Lisa M. Saksida
ArticleOpen Access10 Mar 2021 Scientific Reports
Recording site placement on planar silicon-based probes affects signal quality in acute neuronal recordings
- Richárd Fiáth
- Domokos Meszéna
- István Ulbert
ArticleOpen Access21 Jan 2021 Scientific Reports
Amplification of potential thermogenetic mechanisms in cetacean brains compared to artiodactyl brains
- Paul R. Manger
- Nina Patzke
- Kjell Fuxe
ArticleOpen Access9 Mar 2021 Scientific Reports
Maternal stress during pregnancy alters fetal cortico-cerebellar connectivity in utero and increases child sleep problems after birth
- Marion I. van den Heuvel
- Jasmine L. Hect
- Moriah E. Thomason
ArticleOpen Access26 Jan 2021 Scientific Reports
An anomaly detection approach to identify chronic brain infarcts on MRI
- Kees M. van Hespen
- Jaco J. M. Zwanenburg
- Hugo J. Kuijf
ArticleOpen Access8 Apr 2021 Scientific Reports
The neurodynamic treatment induces biological changes in sensory and motor neurons in vitro
- Giacomo Carta
- Giovanna Gambarotta
- Federica Fregnan
ArticleOpen Access24 Jun 2021 Scientific Reports
Optimal flickering light stimulation for entraining gamma waves in the human brain
- Kanghee Lee
- Yeseung Park
- Ki Woong Kim
ArticleOpen Access10 Aug 2021 Scientific Reports
Two-photon GCaMP6f imaging of infrared neural stimulation evoked calcium signals in mouse cortical neurons in vivo
- Attila Kaszas
- Gergely Szalay
- David Moreau
ArticleOpen Access7 May 2021 Scientific Reports
The Aβ(1–38) peptide is a negative regulator of the Aβ(1–42) peptide implicated in Alzheimer disease progression
- Maa O. Quartey
- Jennifer N. K. Nyarko
- Darrell D. Mousseau
ArticleOpen Access11 Jan 2021 Scientific Reports
Drinking coffee enhances neurocognitive function by reorganizing brain functional connectivity
- Hayom Kim
- Sung Hoon Kang
- Jung Bin Kim
ArticleOpen Access13 Jul 2021 Scientific Reports
The impact of multisensory integration and perceptual load in virtual reality settings on performance, workload and presence
- Matteo Marucci
- Gianluca Di Flumeri
- Pietro Aricò
ArticleOpen Access1 Mar 2021 Scientific Reports
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1^G93A mice with a C57BL/6 background
- Jeremy S. Lum
- Mikayla L. Brown
- Justin J. Yerbury
ArticleOpen Access29 Sep 2021 Scientific Reports
Underlying neurological mechanisms associated with symptomatic convergence insufficiency
- Tara L. Alvarez
- Mitchell Scheiman
- Bharat B. Biswal
ArticleOpen Access22 Mar 2021 Scientific Reports
Paternal exposure to a common pharmaceutical (Ritalin) has transgenerational effects on the behaviour of Trinidadian guppies
- Alex R. De Serrano
- Kimberly A. Hughes
- F. Helen Rodd
ArticleOpen Access17 Feb 2021 Scientific Reports
Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT_2A receptor activation
- April Contreras
- Matthew Khumnark
- Dustin J. Hines
ArticleOpen Access21 Jan 2021 Scientific Reports
Focused ultrasound mediated blood–brain barrier opening is safe and feasible in a murine pontine glioma model
- Zachary K. Englander
- Hong-Jian Wei
- Cheng-Chia Wu
ArticleOpen Access22 Mar 2021 Scientific Reports

76-100

Basmisanil, a highly selective GABA_A-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
- Joerg F. Hipp
- Frederic Knoflach
- Maria-Clemencia Hernandez
ArticleOpen Access8 Apr 2021 Scientific Reports
Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model
- Shinwoo Kang
- Jinho Kim
- Keun-A Chang
ArticleOpen Access14 Jan 2021 Scientific Reports
The gut microbiome is associated with brain structure and function in schizophrenia
- Shijia Li
- Jie Song
- Kai Wu
ArticleOpen Access7 May 2021 Scientific Reports
Static and dynamic functional connectivity supports the configuration of brain networks associated with creative cognition
- Abhishek Uday Patil
- Sejal Ghate
- Chih-Mao Huang
ArticleOpen Access8 Jan 2021 Scientific Reports
Digital signatures for early traumatic brain injury outcome prediction in the intensive care unit
- Anil K. Palepu
- Aditya Murali
- Robert D. Stevens
ArticleOpen Access7 Oct 2021 Scientific Reports
LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1
- Ramona M. Rodriguiz
- Vineet Nadkarni
- William C. Wetsel
ArticleOpen Access3 Sep 2021 Scientific Reports
Modified wavelet analysis of ECoG-pattern as promising tool for detection of the blood–brain barrier leakage
- Anastasiya Runnova
- Maksim Zhuravlev
- Jurgen Kurths
ArticleOpen Access16 Sep 2021 Scientific Reports
Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization
- Hiromu Monai
- Shinnosuke Koketsu
- Hajime Hirase
ArticleOpen Access14 Apr 2021 Scientific Reports
An atlas for human brain myelin content throughout the adult life span
- Adam V. Dvorak
- Taylor Swift-LaPointe
- Shannon H. Kolind
ArticleOpen Access11 Jan 2021 Scientific Reports
Immediate and after effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex
- Carlos A. Sánchez-León
- Isabel Cordones
- Javier Márquez-Ruiz
ArticleOpen Access4 Feb 2021 Scientific Reports
Human brain dynamics in active spatial navigation
- Tien-Thong Nguyen Do
- Chin-Teng Lin
- Klaus Gramann
ArticleOpen Access22 Jun 2021 Scientific Reports
Reading without phonology: ERP evidence from skilled deaf readers of Spanish
- Brendan Costello
- Sendy Caffarra
- Manuel Carreiras
ArticleOpen Access4 Mar 2021 Scientific Reports
Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals
- Soumya Ravichandran
- Ravi R. Bhatt
- Arpana Gupta
ArticleOpen Access9 Feb 2021 Scientific Reports
Disease progression modelling from preclinical Alzheimer’s disease (AD) to AD dementia
- Soo Hyun Cho
- Sookyoung Woo
- Sang Won Seo
ArticleOpen Access18 Feb 2021 Scientific Reports
The structure dilemma in biological and artificial neural networks
- Thomas Pircher
- Bianca Pircher
- Andreas Feigenspan
ArticleOpen Access10 Mar 2021 Scientific Reports
Voluntary intake of psychoactive substances is regulated by the dopamine receptor Dop1R1 in Drosophila
- Mai Kanno
- Shun Hiramatsu
- Toshiharu Ichinose
ArticleOpen Access9 Feb 2021 Scientific Reports
The contribution of platelets to peripheral BDNF elevation in children with autism spectrum disorder
- Cristan A. Farmer
- Audrey E. Thurm
- Joan C. Han
ArticleOpen Access13 Sep 2021 Scientific Reports
Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease
- Victoria Monge-Fuentes
- Andréia Biolchi Mayer
- Márcia Renata Mortari
ArticleOpen Access26 Jul 2021 Scientific Reports
NK1 antagonists attenuate tau phosphorylation after blast and repeated concussive injury
- Frances Corrigan
- Ibolja Cernak
- Robert Vink
ArticleOpen Access23 Apr 2021 Scientific Reports
Nicotine suppresses Parkinson’s disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels
- Angel Carvajal-Oliveros
- Carmen Domínguez-Baleón
- Enrique Reynaud
ArticleOpen Access5 May 2021 Scientific Reports
Free-water diffusion tensor imaging improves the accuracy and sensitivity of white matter analysis in Alzheimer’s disease
- Maurizio Bergamino
- Ryan R. Walsh
- Ashley M. Stokes
ArticleOpen Access26 Mar 2021 Scientific Reports
A functional spiking neuronal network for tactile sensing pathway to process edge orientation
- Adel Parvizi-Fard
- Mahmood Amiri
- Nitish V. Thakor
ArticleOpen Access14 Jan 2021 Scientific Reports
The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells
- Kim Le Cann
- Alec Foerster
- Angelika Lampert
ArticleOpen Access25 Mar 2021 Scientific Reports
Hippocampus-retrosplenial cortex interaction is increased during phasic REM and contributes to memory consolidation
- Daniel Gomes de Almeida-Filho
- Bruna Del Vechio Koike
- Claudio Marcos Queiroz
ArticleOpen Access22 Jun 2021 Scientific Reports
Machine learning-based classification of mitochondrial morphology in primary neurons and brain
- Garrett M. Fogo
- Anthony R. Anzell
- Thomas H. Sanderson
ArticleOpen Access4 Mar 2021 Scientific Reports

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