Gut-brain axis

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Our understanding of the gut-brain axis, the complex bi-directional communication network which links the central nervous system to peripheral intestinal functions, and specifically the integral role played by the gut microbiome, has significantly advanced in recent years. Critical gaps of knowledge however do still exist, particularly with regard to the precise mechanisms of information transmission.

This Collection aims to bring together original research on all aspects of gut-brain communication, including the neural, endocrine and immune pathways involved, and their relevance to the development, and potential mitigation, of neurological, gastrointestinal and behavioural pathologies.

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Brown brain and organe intestinal system connected by a helical cord.


Submitting a paper for consideration


To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Gut-brain axis" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.

Accepted papers are published on a rolling basis as soon as they are ready.

In addition to papers on Gut-brain axis, Scientific Reports welcomes all original research in microbiology. To browse our latest articles in microbiology click here.


Find out more about the Guest Editors here