Reproductive aging

Reproductive aging directly impacts public health, family planning, and quality of life. Understanding the biological mechanisms of reproductive aging can lead to improved fertility treatments and interventions, offering hope to individuals facing age-related infertility. Reproductive aging research can also help mitigate risks associated with late pregnancies, enhance prenatal care, and address age-related reproductive health issues. Moreover, reproductive aging effects extend far beyond age-related fertility declines, as it is intricately associated with systemic health. As individuals age, changes in reproductive hormones can significantly impact various physiological systems. For instance, the decline in estrogen during menopause is associated with increased risks of cardiovascular disease, osteoporosis, and metabolic disorders. Similarly, age-related decreases in testosterone can affect muscle mass, bone density, and mental health in men. Delving into the mechanisms regulating aging in reproductive tissues and their relationship to overall organismal healthspan and longevity is essential for developing comprehensive healthcare strategies that address these broader health issues.

This collection invites research addressing the molecular bases of reproductive longevity, focusing on delaying reproductive decline and curtailing its negative health consequences. Topics of interest include the identification of molecular and cellular mechanisms that regulate aging in reproductive organs and their role in systemic aging.