Cardiovascular disease (CVD) accounts for one-third of deaths worldwide. Atherosclerosis, characterized by a buildup of fatty deposits in arterial walls, is the dominant cause of CVD, including myocardial infarction, stroke, heart failure, and peripheral artery disease. Atherosclerosis is a complex immuno-metabolic disease that develops slowly and has a lifelong progression. Multiple risk factors are linked to atherosclerosis, such as hyperlipidemia, hypertension, diabetes, smoking, obesity, and a sedentary lifestyle.  Although we have witnessed major breakthroughs in the diagnosis and treatment of atherosclerosis in the past few decades, our understanding of the disease’s etiology and pathogenesis is still incomplete, and the need for new diagnostic and therapeutic tools and lifestyle adjustments remains. This collection highlights the breadth of atherosclerosis research published in Nature Cardiovascular Research, and accompanies Gordon Research Conference on Atherosclerosis “Molecular Mechanisms, Genomic Modifiers and Emerging Therapies”.

All articles have undergone Nature Cardiovascular Research’s standard peer review process and have been subject to all of the journal’s standard policies. For more information, refer to our Collections guidelines.

The pathogenesis and treatments of atherosclerosis


  • Vesna Todorović

    Chief Editor, Nature Cardiovascular Research

  • Elvira Forte

    Senior Editor, Nature Cardiovascular Research

  • Gerburg Schwärzer

    Associate Editor, Nature Cardiovascular Research

Research Articles

Review Articles