Supplements

Molecular cancer diagnostics

Vol. 452, No. 7187 pp 547–589

In this supplement

• Editorial
• Overview
• Reviews

The technological advances of the past decade have helped researchers to characterize the molecular basis of cancer. With this knowledge, drugs targeted at specific molecules have been designed. New diagnostics, or biomarkers, for cancer are now urgently needed to determine which of these new drugs a patient is most likely to benefit from.

Editorial

Molecular cancer diagnostics

Barbara Marte, Alex Eccleston & Deepa Nath

doi:10.1038/452547a

Full Text | PDF (89KB)

Overview

The cancer biomarker problem

Charles L. Sawyers

doi:10.1038/nature06913

Abstract | Full Text | PDF (321KB)

Reviews

Translating insights from the cancer genome into clinical practice

Lynda Chin & Joe W. Gray

doi:10.1038/nature06914

Abstract | Full Text | PDF (1,024KB)

Enabling personalized cancer medicine through analysis of gene-expression patterns

Laura J. van 't Veer & Ren� Bernards

doi:10.1038/nature06915

Abstract | Full Text | PDF (756KB)

Mining the plasma proteome for cancer biomarkers

Samir M. Hanash, Sharon J. Pitteri & Vitor M. Faca

doi:10.1038/nature06916

Abstract | Full Text | PDF (1,256KB)

Imaging in the era of molecular oncology

Ralph Weissleder & Mikael J. Pittet

doi:10.1038/nature06917

Abstract | Full Text | PDF (1,763KB)