Collection Scope
Disordered sleep is associated with harmful metabolic changes that can impact health and even promote the development of certain diseases. Chronic sleep deprivation increases the risk of insulin resistance and type 2 diabetes, while sleep disorders like insomnia, sleep apnea, and circadian rhythm disruption are linked to altered glucose, amino acid, and lipid metabolism. Intriguingly, many of the metabolic changes associated with sleep loss are also characteristic of ageing and of neurodegenerative conditions like Alzheimer’s disease. Papers in this Collection will aim to explore the relationship between sleep and metabolism, and how metabolism mediates the relationship between sleep and health.