Diet and systemic metabolism

Systemic and cellular metabolism are to a large degree controlled by nutrition and diet. Metabolic syndrome and obesity can be fuelled by a poor diet, and obesity is associated with an increased risk of cancer. Because rates of obesity and the incidence of metabolic syndrome are increasing world-wide, a large number of prospective patients with cancer are likely to suffer from metabolic syndrome, involving high levels of blood sugar and triglycerides and insulin resistance. How diet and systemic metabolism in health and metabolic disease impact tumour development, progression and metabolism is an area of increasing research interest which could lead to improved therapeutic strategies, including dietary intervention. This series of articles explores recent advances in our understanding of tumour metabolism and growth in the context of systemic regulation, diet and metabolic disease.

A triangle showing a human body in one corner, foods in one corner and cancer cells in the third corner, all connected by arrows as a cycle