The Burden of Proof Studies

The Burden of Proof Studies from the Institute of Health Metrics and Evaluation provide a new method for assessing the cumulative strength of available evidence for risk factors and associated health outcomes. Intended to complement existing tools for assessing evidence these studies will inform development clinical guidelines and health policy.

In this Collection, we present the Capstone Methods paper, as well as analyses that assess the strength of evidence for selected risk-outcome pairs. The Collection will be updated as additional Burden of Proof studies are published in Nature Portfolio journals.

The magnifying glass in the image represents the burden of proof risk function, which enables a closer view of risk factors and the evidence for associated health outcomes.




Methods Capstone

Risk-Outcome Analyses