Glia in health and disease
- Submission status
- Closed
- Submission deadline
Long thought to serve a passive role in the central nervous system (CNS), glial cells are now recognised to actively support neurons in brain development and function, whilst also supporting nervous system homeostasis. At least half the volume of the brain is made up of glial cells—oligodendrocytes, astrocytes, microglia and nerve glial antigen cells. Glia also serve important functions outside of the brain, for instance, enteric glia, a lesser-studied sub-population of glia that reside in the walls of the gut, have emerged as essential regulators of gastrointestinal functions. However, fundamental questions remain about several aspects of their biology. Perturbation of glial function characterises a multitude of brain disorders and gastrointestinal diseases, from Multiple Sclerosis, Amyotrophic lateral sclerosis, Alzheimer’s disease, to autism and glioma, yet a complete appreciation of the underlying pathophysiology is lacking. A more holistic picture of all players of the CNS will contribute to a deeper mechanistic understanding of neurological disorders, that is essential for devising successful therapeutic interventions.
This Collection invites original articles which describe new experimental models and tools to study glial function, as well as submissions that advance our understanding of their roles in health and disease.
Editors
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Ruben J. Cauchi
University of Malta, Malta
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Nicolas Dzamko
The University of Sydney, Australia
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Maura Francolini
University of Milan, Italy
Submitting a paper for consideration
To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Glia in health and disease" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.
Accepted papers are published on a rolling basis as soon as they are ready.
In addition to papers on Glia in health and disease, Scientific Reports welcomes all original research in the field of Cell biology. To browse our latest articles in Cell biology click here.
