Bone Research

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The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

Heeseog Kang
Amy L. Strong
Benjamin Levi

Article 12 March 2024

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Sorafenib inhibits ossification of the posterior longitudinal ligament by blocking LOXL2-mediated vascularization

Longqing Wang
Wenhao Jiang
Lili Yang
ArticleOpen Access10 Apr 2024
Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and pain

Feng Gao
Qimiao Hu
Xu Cao
ArticleOpen Access05 Mar 2024
Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development

Laura J. Brylka
Assil-Ramin Alimy
Thorsten Schinke
ArticleOpen Access23 Feb 2024

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Behind the Paper

Behind the Paper is a channel for researchers to share the real stories behind the latest research papers, from conception to publication, the highs and the lows. We welcome our authors to share the methods they used to conduct their studies, as well as experiences of collaborating with other teams and across disciplines.

Browse articles

Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome

Yanqiu Wang
Wanqian Zhang
Minghan Liu
ArticleOpen Access06 Sept 2024
Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects

Zhenqiang Yao
Akram Ayoub
Brendan F. Boyce
ArticleOpen Access05 Sept 2024
Bone targeted nano-drug and nano-delivery

Yilun Wu
Bing Sun
Wenyi Gu
Review ArticleOpen Access04 Sept 2024
Targeting Fascin1 maintains chondrocytes phenotype and attenuates osteoarthritis development

Panpan Yang
Yun Xiao
Kai Li
ArticleOpen Access04 Sept 2024
Osteoclasts control endochondral ossification via regulating acetyl-CoA availability

Daizhao Deng
Xianming Liu
Yue Zhang
ArticleOpen Access28 Aug 2024
The HOXC10/NOD1/ERK axis drives osteolytic bone metastasis of pan-KRAS-mutant lung cancer

Kun Li
Bo Yang
Lei Li
ArticleOpen Access27 Aug 2024
SREBP2 restricts osteoclast differentiation and activity by regulating IRF7 and limits inflammatory bone erosion

Haemin Kim
In Ah Choi
Kyung-Hyun Park-Min
ArticleOpen Access27 Aug 2024
Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta

Na Li
Baohong Shi
Ren Xu
ArticleOpen Access26 Aug 2024
Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice

Ziwei Luo
Wanyi Wei
Li Yang
ArticleOpen Access21 Aug 2024

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