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Allogeneic peripheral blood cell transplantation for hypereosinophilic syndrome with myelofibrosis

Bone Marrow Transplantation volume 25, pages 217–218 (2000)Cite this article

Abstract

Patients with hypereosinophilic syndrome (HES) display a very heterogeneous clinical picture ranging from asymptomatic cases to very aggressive forms. We report a 38-year-old woman with progressive HES who developed severe myelofibrosis and was treated by allogeneic stem cell transplantation, using peripheral blood (PBSCT) instead of bone marrow as the source of progenitor cells, after conditioning with cytoxan and busulphan. To the best of our knowledge, this is the first case of HES with myelofibrosis treated with PBSCT. The patient remains alive 8 months post-PBSCT, and bone marrow fibrosis has significantly decreased following transplantation. Bone Marrow Transplantation (2000) 25, 217–218.

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Acknowledgements

The authors thank Mark Anderson for his technical assistance.

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Authors and Affiliations

  1. Hematology Service, University Hospital of Salamanca,

    L Vazquez, D Caballero, C Del Cañizo, C Lopez, R Hernandez, I Gonzalez, T Flores & JF San Miguel

  2. Centro de Investigación del Cancer (CIC), University of Salamanca, CSIC, Spain

    L Vazquez, D Caballero, C Del Cañizo, C Lopez, R Hernandez, I Gonzalez, T Flores & JF San Miguel

Authors
  1. L Vazquez
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  2. D Caballero
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  3. C Del Cañizo
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  4. C Lopez
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  5. R Hernandez
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  6. I Gonzalez
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  7. T Flores
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  8. JF San Miguel
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Vazquez, L., Caballero, D., Del Cañizo, C. et al. Allogeneic peripheral blood cell transplantation for hypereosinophilic syndrome with myelofibrosis. Bone Marrow Transplant 25, 217–218 (2000). https://doi.org/10.1038/sj.bmt.1702102

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  • DOI: https://doi.org/10.1038/sj.bmt.1702102

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