Genetics and Genomics

Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel

• Ceres Fernandez-Rozadilla
• Christiana Kartsonaki
• Ian Tomlinson

A core matrisome gene signature predicts cancer outcome

• Arseniy E Yuzhalin
• Tomas Urbonas
• Alex N Gordon-Weeks

MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours

• Diego A Garcia-Dios
• Dina Levi
• Elinor J Sawyer

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition

• Christos Mikropoulos
• Christina G Hutten Selkirk
• Rosalind A Eeles

Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer

• Higinio Dopeso
• Paulo Rodrigues
• Diego Arango

Global metabolomic profiling of uterine leiomyomas

• Hanna-Riikka Heinonen
• Miika Mehine
• Eevi Kaasinen

Towards gene- and gender-based risk estimates in Lynch syndrome; age-specific incidences for 13 extra-colorectal cancer types

• Christina Therkildsen
• Steen Ladelund
• Mef Nilbert

Clinically significant mutations in HIV-infected patients with lung adenocarcinoma

• Jonathan Thaler
• Carlie Sigel
• Keith Sigel

Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults

• Xu Gao
• Yan Zhang
• Hermann Brenner

Characterisation of the novel deleterious RAD51C p.Arg312Trp variant and prioritisation criteria for functional analysis of RAD51C missense changes

• Javier Gayarre
• Paloma Martín-Gimeno
• María J García

Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma

• Jen Y Lee
• Isaac Garcia-Murillas
• Shreerang Bhide

GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi

• M J C Vader
• M C Madigan
• P A van der Velden

A comparative study of germline BRCA1 and BRCA2 mutation screening methods in use in 20 European clinical diagnostic laboratories

• Gillian Ellison
• Andrew Wallace
• Simon Patton

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia

• Stephanie A Schubert
• Dina Ruano
• Tom van Wezel

Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma

• Sarah Schumacher
• Christoph Bartenhagen
• Birte Möhlendick

Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma

• Hiroaki Itamochi
• Tetsuro Oishi
• Toru Sugiyama

Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

• Michael T Barrett
• Ray Deiotte
• Daniel D Von Hoff

Non-invasive prediction of recurrence in bladder cancer by detecting somatic TERT promoter mutations in urine

• Françoise Descotes
• Norelyakin Kara
• Alain Ruffion

Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component

• M Henar Alonso
• Susanna Aussó
• Victor Moreno

Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer

• Yusuke Goto
• Akira Kurozumi
• Naohiko Seki