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Editorial |
When less is more: regarding the use of chest X-ray instead of computed tomography in screening for pulmonary metastasis in postmolar gestational trophoblastic neoplasia
- Antonio Braga
- , Kevin Meyer Elias
- , Neil Stuart Horowitz
- & Ross Stuart Berkowitz
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Article
| Open AccessLack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis
- Richard Culliford
- , Alex J. Cornish
- , Philip J. Law
- , Susan M. Farrington
- , Kimmo Palin
- , Mark A. Jenkins
- , Graham Casey
- , Michael Hoffmeister
- , Hermann Brenner
- , Jenny Chang-Claude
- , Iva Kirac
- , Tim Maughan
- , Stefanie Brezina
- , Andrea Gsur
- , Jeremy P. Cheadle
- , Lauri A. Aaltonen
- , Malcom G. Dunlop
- & Richard S. Houlston
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Article |
Multi-protein spatial signatures in ductal carcinoma in situ (DCIS) of breast
- Sunil S. Badve
- , Sanghee Cho
- , Yesim Gökmen-Polar
- , Yunxia Sui
- , Chrystal Chadwick
- , Elizabeth McDonough
- , Anup Sood
- , Marian Taylor
- , Maria Zavodszky
- , Puay Hoon Tan
- , Michael Gerdes
- , Adrian L. Harris
- & Fiona Ginty
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Article
| Open AccessPrognostic value of desmoplastic reaction characterisation in stage II colon cancer: prospective validation in a Phase 3 study (SACURA Trial)
- Hideki Ueno
- , Megumi Ishiguro
- , Eiji Nakatani
- , Toshiaki Ishikawa
- , Hiroyuki Uetake
- , Kenta Murotani
- , Shigeyuki Matsui
- , Satoshi Teramukai
- , Tamotsu Sugai
- , Yoichi Ajioka
- , Hirotoshi Maruo
- , Masahito Kotaka
- , Masaki Tsujie
- , Yoshinori Munemoto
- , Takashi Yamaguchi
- , Hisashi Kuroda
- , Mutsumi Fukunaga
- , Naohiro Tomita
- & Kenichi Sugihara
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Article
| Open AccessThe effectiveness of the Guy’s Rapid Diagnostic Clinic (RDC) in detecting cancer and serious conditions in vague symptom patients
- Saoirse Olivia Dolly
- , Geraint Jones
- , Paula Allchorne
- , Daniel Wheeler
- , Sunnyath Ali
- , Yaseen Mukadam
- , Sifan Zheng
- , Loay Rahman
- , Jan Sindhar
- , Charlotte Louise Moss
- , Danielle Harari
- , Mieke Van Hemelrijck
- , Anthony Cunliffe
- & Luigi Vincenzo De Michele
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Article
| Open AccessThe mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes
- Diego Salas-Benito
- , Enrique Conde
- , Ibon Tamayo-Uria
- , Uxua Mancheño
- , Edurne Elizalde
- , David Garcia-Ros
- , Jose M. Aramendia
- , Juan C. Muruzabal
- , Julia Alcaide
- , Francisco Guillen-Grima
- , Jose A. Minguez
- , Jose Amores-Tirado
- , Antonio Gonzalez-Martin
- , Pablo Sarobe
- , Juan J. Lasarte
- , Mariano Ponz-Sarvise
- , Carlos E. De Andrea
- & Sandra Hervas-Stubbs
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Comment |
Time to revisit the use of G-CSF after allogeneic haematopoietic cell transplantation in COVID-19 era?
- Alexandre E. Malek
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Article |
Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy
- Robyn V. Broad
- , Stacey J. Jones
- , Melina C. Teske
- , Laura M. Wastall
- , Andrew M. Hanby
- , James L. Thorne
- & Thomas A. Hughes
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Article
| Open AccessBiomarkers for site-specific response to neoadjuvant chemotherapy in epithelial ovarian cancer: relating MRI changes to tumour cell load and necrosis
- Jessica M. Winfield
- , Jennifer C. Wakefield
- , James D. Brenton
- , Khalid AbdulJabbar
- , Antonella Savio
- , Susan Freeman
- , Erika Pace
- , Kerryn Lutchman-Singh
- , Katherine M. Vroobel
- , Yinyin Yuan
- , Susana Banerjee
- , Nuria Porta
- , Shan E. Ahmed Raza
- & Nandita M. deSouza
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Article
| Open AccessDairy intake during adolescence and risk of colorectal adenoma later in life
- Katharina Nimptsch
- , Dong Hoon Lee
- , Xuehong Zhang
- , Mingyang Song
- , Maryam S. Farvid
- , Leandro F. M. Rezende
- , Yin Cao
- , Andrew T. Chan
- , Charles Fuchs
- , Jeffrey Meyerhardt
- , Jonathan A. Nowak
- , Walter C. Willett
- , Shuji Ogino
- , Edward Giovannucci
- , Tobias Pischon
- & Kana Wu
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Article |
Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial
- Arinilda Campos Bragagnoli
- , Raphael L. C. Araujo
- , Mauricio Wagner Ferraz
- , Lucas Vieira dos Santos
- , Kathia Cristina Abdalla
- , Fabiana Comar
- , Florinda Almeida Santos
- , Marco Antonio Oliveira
- , José Barreto Campello Carvalheira
- , Flávio Mavigner Cárcano
- & João Paulo da Silveira Nogueira Lima
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Correspondence |
Comment on “Heterogeneity in PD-L1 expression in malignant peritoneal mesothelioma with systemic or intraperitoneal chemotherapy”
- Haitang Yang
- , Sean R. R. Hall
- , Beibei Sun
- & Feng Yao
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Article
| Open AccessSLFN11 informs on standard of care and novel treatments in a wide range of cancer models
- Claudia Winkler
- , Joshua Armenia
- , Gemma N. Jones
- , Luis Tobalina
- , Matthew J. Sale
- , Tudor Petreus
- , Tarrion Baird
- , Violeta Serra
- , Anderson T. Wang
- , Alan Lau
- , Mathew J. Garnett
- , Patricia Jaaks
- , Elizabeth A. Coker
- , Andrew J. Pierce
- , Mark J. O’Connor
- & Elisabetta Leo
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Article |
Comprehensive analysis of the 21-gene recurrence score in invasive ductal breast carcinoma with or without ductal carcinoma in situ component
- Yufei Zeng
- , Weiqi Gao
- , Xiaosong Chen
- & Kunwei Shen
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Editorial |
The role of Schlafen 11 (SLFN11) as a predictive biomarker for targeting the DNA damage response
- Niamh Coleman
- , Bingnan Zhang
- , Lauren A. Byers
- & Timothy A. Yap
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Article |
Computed tomography chest imaging offers no advantage over chest X-ray in the initial assessment of gestational trophoblastic neoplasia
- Victoria L. Parker
- , Matthew C. Winter
- , Elspeth Whitby
- , William A. E. Parker
- , Julia E. Palmer
- , John A. Tidy
- , Allan A. Pacey
- , Barry W. Hancock
- & Robert F. Harrison
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Correspondence |
Response to Comment on “Heterogeneity in PD-L1 expression in malignant peritoneal mesothelioma with systemic or intraperitoneal chemotherapy”
- Michael G. White
- & Oliver S. Eng
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Correspondence |
Comment on “Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes”
- Maurice B. Loughrey
- , Natalie C. Fisher
- , Aoife J. McCooey
- & Philip D. Dunne
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Article |
Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax
- Lee-or Herzog
- , Beth Walters
- , Roberta Buono
- , J. Scott Lee
- , Sharmila Mallya
- , Amos Fung
- , Honyin Chiu
- , Nancy Nguyen
- , Boyang Li
- , Anthony B. Pinkerton
- , Michael R. Jackson
- , Robert J. Schneider
- , Ze’ev A. Ronai
- & David A. Fruman
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Article
| Open AccessA Phase 1 study of RO6870810, a novel bromodomain and extra-terminal protein inhibitor, in patients with NUT carcinoma, other solid tumours, or diffuse large B-cell lymphoma
- Geoffrey I. Shapiro
- , Patricia LoRusso
- , Afshin Dowlati
- , Khanh T. Do
- , Caron A. Jacobson
- , Ulka Vaishampayan
- , Amy Weise
- , Paolo F. Caimi
- , Joseph Paul Eder
- , Christopher A. French
- , Emily Labriola-Tompkins
- , Frédéric Boisserie
- , William E. Pierceall
- , Jianguo Zhi
- , Sharon Passe
- , Mark DeMario
- , Martin Kornacker
- & Philippe Armand
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Article |
Phosphorylation-dependent regulation of SPOP by LIMK2 promotes castration-resistant prostate cancer
- Kumar Nikhil
- , Hanan S. Haymour
- , Mohini Kamra
- & Kavita Shah
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Article |
Tumour-free distance: a novel prognostic marker in patients with early-stage cervical cancer treated by primary surgery
- David Cibula
- , Jiri Slama
- , Lukáš Dostálek
- , Daniela Fischerová
- , Anna Germanova
- , Filip Frühauf
- , Pavel Dundr
- , Kristyna Nemejcova
- , Jiri Jarkovsky
- , Silvie Sebestova
- , Andrea Burgetová
- , Martina Borčinová
- & Roman Kocián
-
Article
| Open AccessSeverity of COVID-19 in children with cancer: Report from the United Kingdom Paediatric Coronavirus Cancer Monitoring Project
- Gerard C. Millen
- , Roland Arnold
- , Jean-Baptiste Cazier
- , Helen Curley
- , Richard G. Feltbower
- , Ashley Gamble
- , Adam W. Glaser
- , Richard G. Grundy
- , Lennard Y. W. Lee
- , Martin G. McCabe
- , Robert S. Phillips
- , Charles A. Stiller
- , Csilla Várnai
- & Pamela R. Kearns
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Article |
Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma
- Yang Liu
- , Yoshifumi Baba
- , Takatsugu Ishimoto
- , Hiroyasu Tsutsuki
- , Tianli Zhang
- , Daichi Nomoto
- , Kazuo Okadome
- , Kensuke Yamamura
- , Kazuto Harada
- , Kojiro Eto
- , Yukiharu Hiyoshi
- , Masaaki Iwatsuki
- , Yohei Nagai
- , Shiro Iwagami
- , Yuji Miyamoto
- , Naoya Yoshida
- , Yoshihiro Komohara
- , Masaki Ohmuraya
- , Xiaoming Wang
- , Jaffer A. Ajani
- , Tomohiro Sawa
- & Hideo Baba
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Article |
Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts
- Ryoji Kato
- , Koji Haratani
- , Hidetoshi Hayashi
- , Kazuko Sakai
- , Hitomi Sakai
- , Hisato Kawakami
- , Kaoru Tanaka
- , Masayuki Takeda
- , Kimio Yonesaka
- , Kazuto Nishio
- & Kazuhiko Nakagawa
-
Article
| Open AccessEMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures
- Suhas V. Vasaikar
- , Abhijeet P. Deshmukh
- , Petra den Hollander
- , Sridevi Addanki
- , Nick Allen Kuburich
- , Sriya Kudaravalli
- , Robiya Joseph
- , Jeffrey T. Chang
- , Rama Soundararajan
- & Sendurai A. Mani
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Article
| Open AccessExploring the impact of cancer registry completeness on international cancer survival differences: a simulation study
- Therese M.-L. Andersson
- , Mark J. Rutherford
- , Tor Åge Myklebust
- , Bjørn Møller
- , Isabelle Soerjomataram
- , Melina Arnold
- , Freddie Bray
- , D. Max Parkin
- , Peter Sasieni
- , Oliver Bucher
- , Prithwish De
- , Gerda Engholm
- , Anna Gavin
- , Alana Little
- , Geoff Porter
- , Agnihotram V. Ramanakumar
- , Nathalie Saint-Jacques
- , Paul M. Walsh
- , Ryan R. Woods
- & Paul C. Lambert
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Editorial
| Open AccessSummary of ‘The current status and future perspectives on the management of stage III NSCLC: a focus on unresectable cancer treatment paradigms’
- Luis Paz-Ares
-
Editorial
| Open AccessForeword to ‘The current status and future perspectives on the management of stage III NSCLC: a focus on unresectable cancer treatment paradigms’
- Luis Paz-Ares
-
Brief Communication |
Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer
- Shiqin Liu
- , Michelle Shen
- , En-Chi Hsu
- , Chiyuan Amy Zhang
- , Fernando Garcia-Marques
- , Rosalie Nolley
- , Kashyap Koul
- , Meghan A. Rice
- , Merve Aslan
- , Sharon J. Pitteri
- , Charlie Massie
- , Anne George
- , James D. Brooks
- , Vincent J. Gnanapragasam
- & Tanya Stoyanova
-
Mini Review
| Open AccessRationale for concurrent chemoradiotherapy for patients with stage III non-small-cell lung cancer
- John Conibear
-
Mini Review
| Open AccessThe current treatment landscape in the UK for stage III NSCLC
- Matthew Evison
-
Mini Review
| Open AccessBeyond chemoradiotherapy: improving treatment outcomes for patients with stage III unresectable non-small-cell lung cancer through immuno-oncology and durvalumab (Imfinzi®▼, AstraZeneca UK Limited)
- Priyanka Patel
- , Doraid Alrifai
- , Fiona McDonald
- & Martin Forster
-
Mini Review
| Open AccessPractical implications to contemplate when considering radical therapy for stage III non-small-cell lung cancer
- Claire L. Storey
- , Gerard G. Hanna
- & Alastair Greystoke
-
Comment
| Open AccessCOVID-19 vaccine race: watch your step for cancer patients
- Raphaelle Fanciullino
- , Joseph Ciccolini
- & Gerard Milano
-
Correction
| Open AccessCorrection: A balance score between immune stimulatory and suppressive microenvironments identifies mediators of tumour immunity and predicts pan-cancer survival
- Tolga Turan
- , Sarah Kongpachith
- , Kyle Halliwill
- , Jessica Roelands
- , Wouter Hendrickx
- , Francesco M. Marincola
- , Thomas J. Hudson
- , Howard J. Jacob
- , Davide Bedognetti
- , Josue Samayoa
- & Michele Ceccarelli
-
Editorial |
Correlation of anti-tumour drug resistance with epigenetic regulation
- Takuma Hayashi
- & Ikuo Konishi
-
Comment |
Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity
- Kalle Gehring
- & Hiroaki Miki
-
Review Article |
Fibroblast growth factor receptors in cancer: genetic alterations, diagnostics, therapeutic targets and mechanisms of resistance
- Melanie A. Krook
- , Julie W. Reeser
- , Gabrielle Ernst
- , Hannah Barker
- , Max Wilberding
- , Gary Li
- , Hui-Zi Chen
- & Sameek Roychowdhury
-
Article
| Open AccessDevelopment and validation of a novel staging system integrating the number and location of lymph nodes for gastric adenocarcinoma
- Ziyu Li
- , Xiaolong Wu
- , Xiangyu Gao
- , Fei Shan
- , Xiangji Ying
- , Yan Zhang
- & Jiafu Ji
-
Review Article |
Endocytosis: a pivotal pathway for regulating metastasis
- Imran Khan
- & Patricia S. Steeg
-
Article |
Metformin use and lung cancer survival: a population-based study in Norway
- Suzan Brancher
- , Nathalie C. Støer
- , Elisabete Weiderpass
- , Ronald A. M. Damhuis
- , Tom B. Johannesen
- , Edoardo Botteri
- & Trond-Eirik Strand
-
Review Article |
Emerging immunotherapies for metastasis
- Sarah C. Edwards
- , Wilma H. M. Hoevenaar
- & Seth B. Coffelt
-
Editorial |
Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer
- Michala Gylling Rolver
- & Stine Falsig Pedersen
-
Brief Communication |
CBL0137 increases the targeting efficacy of Rovalpituzumab tesirine against tumour-initiating cells in small cell lung cancer
- Daniel J. Lindner
- , Gary Wildey
- , Yvonne Parker
- , Afshin Dowlati
- , George R. Stark
- & Sarmishtha De
-
Article |
RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer
- Derek Dustin
- , Guowei Gu
- , Amanda R. Beyer
- , Sarah K. Herzog
- , David G. Edwards
- , Hangqing Lin
- , Thomas L. Gonzalez
- , Sandra L. Grimm
- , Cristian Coarfa
- , Doug W. Chan
- , Beom-Jun Kim
- , Jean-Paul De La O
- , Matthew J. Ellis
- , Dan Liu
- , Shunqiang Li
- , Alana L. Welm
- & Suzanne A. W. Fuqua
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Review Article |
TRAIL receptor-induced features of epithelial-to-mesenchymal transition increase tumour phenotypic heterogeneity: potential cell survival mechanisms
- Ludovic Peyre
- , Mickael Meyer
- , Paul Hofman
- & Jérémie Roux
-
Article
| Open AccessInfiltrating T-cell markers in cervical carcinogenesis: a systematic review and meta-analysis
- Tamara R. Litwin
- , Sarah R. Irvin
- , Rebecca L. Chornock
- , Vikrant V. Sahasrabuddhe
- , Margaret Stanley
- & Nicolas Wentzensen
-
Article
| Open AccessPostoperative, but not preoperative, inflammation-based prognostic markers are prognostic factors in stage III colorectal cancer patients
- Kohei Yasui
- , Dai Shida
- , Yuya Nakamura
- , Yuka Ahiko
- , Shunsuke Tsukamoto
- & Yukihide Kanemitsu