Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 11 Issue 5, November 2017

In this issue...

• Partnering for CNS disorders

• Taking a journey through gene therapy

• How to prepare for a pharmaceutical deal

Cover image: Human brain formed from medical icons. seamartini, Thinkstock.

Volume 11 Issue 5

Preparing for a pharmaceutical deal

Top of page ⤴

Partnering for CNS disorders

  • Feature

    • Despite recent clinical trial failures, there is a robust dealmaking and funding environment for companies tackling diseases of the central nervous system, indicating that eventual success is expected.

      • Chris Morrison
      News Feature
  • Profiles

    • Indivior is investing in research and development to pioneer life-transforming treatments in addiction medicine, and in partnerships worldwide to realize its vision that all patients will have access to quality treatment for the chronic relapsing conditions and co-occurring disorders of addiction.

      • Indivior Inc.
      Advertisement Feature
    • Probiodrug is using a multi-pronged approach to reduce brain levels of pyroglutamate–amyloid-β peptides; results from the SAPHIR IIa trial for the company’s lead candidate PQ912 reveal positive early efficacy data that are highly attractive for further development.

      • Probiodrug AG
      Advertisement Feature
    • BioAxone is developing a suite of game-changing treatments for spinal cord injury, neurovascular diseases, and eye disorders by targeting Rho/Rho kinase signaling pathways involved in a variety of pathological processes.

      • BioAxone BioSciences Inc.
      Advertisement Feature
    • ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration with a robust mechanism of action for improved therapeutic efficacy. The company is looking for partners to codevelop or out-license bispecific antibodies able to penetrate the blood–brain barrier.

      • ABL Bio Inc.
      Advertisement Feature
    • Abide Therapeutics’ lead product ABX-1431, which is about to reach phase 2 trials, is the first drug candidate to emerge from Abide’s unique platform for generating first-in-class serine-hydrolase-targeted therapeutics.

      • Abide Therapeutics
      Advertisement Feature
    • With several products in advanced clinical stages, such as oral CGRP-receptor antagonists and glutamate modulators, Biohaven is welcoming collaborations on these programs and broadening its pipeline further.

      • Biohaven Pharmaceuticals, Inc.
      Advertisement Feature
Top of page ⤴

Gene therapy

  • Feature

    • With a pioneering gene therapy now on the brink of approval, this feature highlights some of the key deals and news in the field in the past five years.

      • Biopharma Dealmakers
      News Feature
  • Profiles

    • Aposense is powering drug delivery by means of a recently discovered electrostatic field residing in the phospholipid membrane.

      • Aposense
      Advertisement Feature
    • Brainstorm Cell Therapeutics is looking for financial and corporate partners to help complete the development and launch of revolutionary neurodegenerative disease treatments.

      • Brainstorm Cell Therapeutics Inc.
      Advertisement Feature
    • BrightPath, formerly known as GreenPeptide, is moving beyond peptides to push the boundaries of cancer immunotherapy toward more personalized treatments.

      • BrightPath Biotherapeutics Co., Ltd.
      Advertisement Feature
    • Clinical-stage biopharmaceutical company Fate Therapeutics is creating first-in-class (re)programmed cellular immunotherapies for cancer and immune disorders. Preclinical and clinical development of the company’s product pipeline is driven by a determined pursuit of a new cell therapy paradigm and an expanding array of strategic partnerships to support its innovative mission

      • Fate Therapeutics
      Advertisement Feature
Top of page ⤴

Search

Quick links