Table 7 TCA cycle metabolite differences between study groups at age 18

From: Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort

Metabolite Controls (n=36) (mg l−1) Cases (n=36) (mg l−1) P-value
Citric acid 11.68±5.86 9.43±4.84 0.07
Succinic acid 0.57±0.24 0.46±0.23 0.04
Fumaric acid 0.72±0.08 0.77±0.48 0.69
a-ketoglutaric acid 1.06±0.65 0.87±0.68 0.24
Malic acid 0.47±0.47 0.52±0.47 0.36
  1. Abbreviations: BMI, body mass index; TCA, tricarboxylic acid. P-values are adjusted for gender and BMI.