Table 4 Differential plasma lipids between control and PD groups at age 18

From: Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort

Lipid name Control (n=117) Cases (n=36) P-value FDR-adjusted
LPC(16:0) 848.58±191.96 771.44±227.83 0.0402 0.4042
LPC(16:1) 37.75±6.43 35.03±5.67 0.0319 0.3609
LPC(22:6) 28.63±4.66 25.7±4.46 0.0255 0.4196
PC(31:0) 26.39±7.66 22.9±7.38 0.0136 0.4103
PC(32:1) 281.87±137.89 249.65±106.1 0.0311 0.3752
PC(33:1) 62.63±18.43 54.06±13.57 0.0037 0.2232
PC(35:1) 75.59±21.09 68.31±13.57 0.0405 0.3858
PC(36:2) 67.41±21.4S 62.37±16.45 0.0468 0.385
PC(36:4) 2641.06±637.15 2656.62±708.18 0.0369 0.3929
PC(37:4) 67.93±26.92 59.57±28.94 0.0456 0.4127
PC(38:6) 114.34 ±42.33 109.33±32.87 0.0122 0.4416
PC(40:6) 283.19±122.05 255.9±115.8 0.031 0.4008
PC(40:7) 76±27.51 68.99±23.89 0.0147 0.3801
PC(O-38:4) 100.79±36.03 85.19±33.38 0.0213 0.4283
PC(O-40:6) 34.75±6.81 32.08±6.39 0.0169 0.3823
PC(O-42:3) 29.63±6.56 26.94±7.07 0.047 0.3699
PE(P-18:0/22:6) 35.6±8.05 32.61±7.62 0.0466 0.4016
SM(d18:0/16:0) 890.9±207.12 850.9±189.57 0.0118 0.534
SM(d32:1) 1901.22±547.7 1783.34± 498.81 0.0259 0.3907
SM(d33:1) 1227.82±311.1 1118.09±297.23 0.003 0.2715
TG(49:3) 33.78±1.18 33.31±1.53 0.0242 0.438
TG(51:2) 26.14±3.26 24.06±5.41 0.0024 0.4344
TG(56:7) 106.1±58.84 95.83±76.34 0.0288 0.401
  1. Abbreviations: CE, cholesterol ester; LPC, lysophosphatidylcholine; PC, phosphatidylcholine; PD, psychotic disorder; SM, sphingomyelin; TG, triacylglycerol.
  2. Values are expressed as standard units±s.d. (standard deviation). P-values are adjusted for gender and BMI. FDR-adjusted P-values are adjusted for multiple comparisons using the Benjamini–Hochberg procedure.