Figure 6 | Translational Psychiatry

Figure 6

From: 15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

Figure 6

Cognition in Df(h15q13)−/− mice. (a, b) Morris water maze. n=4–6 for each genotype. (a) Acquisition for six consecutive days, four trials per day, ITI 30 min. Repeated measures ANOVA, P<0.001. Tukey’s multiple comparisons indicated. Mean±s.e.m. (b) Visual trial. Kruskal–Wallis test, P<0.05. Dunn’s multiple comparisons indicated. (c, d) Fear conditioning. N=6–9 females for each genotype. (c) Context fear memory. One-way ANOVA, NS. Mean±s.e.m. (d) Auditory cued fear memory. Kruskal–Wallis test, P<0.05. Dunn’s multiple comparisons indicated. Data presented as mean±s.e.m. *P<0.05; ***P<0.001. ANOVA, analysis of variance; NS, not significant; WT, wildtype.

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