Figure 4

From: Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression

Figure 4

Suicide-induced alterations on the relative proportion of three isoforms of 5-HT2CR mRNA in Brodmann area 9 (BA9). (a) Sum of the relative proportion (%) of the AB, AC and NE 5-HT2CR isoforms in control (n=7) and suicide groups (n=8). (b) The combination of the AB-, AC- and non-edited (NE) isoforms was used to determine the threshold value and the performances of the diagnostic test by mROC. The performances are shown in the insets under the mROC curve.