Figure 2

From: Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression

Figure 2

Relative isoform proportion of 5-HT2CR mRNA in Brodmann area 9 (BA9) measured by capillary electrophoresis single-stranded conformational polymorphism (CE-SSCP) on samples of the control group. (a) Histograms represent relative isoform proportion (%) of the 21 foremost detected 5-HT2CR isoform (means±s.e.m.; n=7). Only isoforms representing more than 0.5% of relative proportion were included in the analysis. (b) Relative distribution of 5-HT2CR mRNA isoforms grouped by the number of ‘edited’ adenosine sites within the studied sequence. Histograms represent the cumulative relative proportion of all isoforms. The complete data set of 5-HT2CR mRNA editing in BA9 and BA24 in control and suicide groups can be found in Supplementary Figure S7.