Figure 1

From: Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy

Figure 1

Correlational expression networks. Co-expression patterns of transcript levels at baseline, normalized to their matched controls (RQ), of subjects remitted (a) and non-remitted (b) after CBT. Two genes were considered to be co-expressed if their Spearman correlation was >0.7 and the test statistics against zero correlation was <0.01. Red lines represent common co-expression of non-remitted and remitted groups, and black lines represent group-specific co-expression. Transcripts showing significantly different levels at baseline between subjects with MDD and ND controls are plotted with filled circles. CBT, cognitive behavioral therapy; MDD, major depressive disorder; ND, nondepressed.